We undertook an analysis of every article in the medical literature that mentioned hypopigmentation and mycosis fungoides (33 in toto). Each article was scrutinized in regard to content, photographs of lesions pictured clinically, and photomicrographs. On the basis of all the information in the 33 publications available to us, we made a determination about which patients had mycosis fungoides without doubt, which surely did not, and which about whom no judgment could be made because too little data requisite for such a decision was provided, especially in terms of clinical photographs and photomicrographs. When, for example, no photomicrographs were published and the description of findings by conventional microscopy was insufficient to permit us to come to a diagnosis with confidence, the patient was not included in this study.