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Dermatopathology: Practical & Conceptual January - March 2006
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5. New Heights: An assist to the next (10th) edition of “Lever’s”
Renata A. Joffe, M.D.
Content
Introduction
1. Small plaque parapsoriasis
2. Dysplastic nevus
3. Solar keratosis
4. Inverted follicular keratosis/trichilemmoma
5. Discoid lupus erythematosus vs. systemic lupus erythematosus
6. Lentigo maligna
7. Atopic dermatitis
8. Sebaceous adenoma
9. Muir-Torre syndrome
10. Bowen’s disease
11. Follicular mucinosis/alopecia mucinosa
12. Granuloma faciale and erythema elevatum diutinum
13. Follicular degeneration syndrome
14. Eccrine papillary adenoma
15. Degos’ disease
16. Dermatofibroma
17. Proliferating tricholemmal cyst
18. Erythema multiforme (dermal and epidermal types)
19. Lichen sclerosus et atrophicus vs. morphea
20. Malignant melanoma (classification)
21. Malignant melanoma—ABCD’s
22. Malignant melanoma—wide/deep excision
23. Sentinel node biopsy for melanoma
24. Malignant melanoma: nontumorigenic compartment of primary malignant melanoma (radial growth phase), tumorigenic compartment of primary malignant melanoma (vertical growth phase)
25. Minimal deviation melanoma
26. Nevoid melanoma
27. Malignant melanoma—in infancy and childhood
28. Malignant blue nevus
29. MELTUMP and SAMPUS
30. Bulge activation hypothesis
Conclusion
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1. Small plaque parapsoriasis
Quotation from the 9th edition of Lever's:
"Relationship with lymphomait is generally accepted that the small plaque parapsoriasis, or digitate dermatosis, is a benign disorder without the potential of transformation into mycosis fungoides."
Reference in the 9th edition to concepts contrary by A. Bernard Ackerman et al. (ABA): None.
Statements contrary by ABA:
"Error: Small-plaque parapsoriasis (digitate and guttate dermatosis) is not mycosis fungoides. Reason: Small-plaque parapsoriasis, like large-plaque parapsoriasis, is a macular/patch expression of mycosis fungoides."
"Error: Some conditions termed parapsoriasis may convert into mycosis fungoides. Reason: Mycosis fungoides is a systemic lymphoma from the outset; small-plaque parapsoriasis, as but one example, cannot transform into mycosis fungoides because it is mycosis fungoides and, in fact, no inflammatory disease converts into mycosis fungoides."
Ackerman AB, Böer A, Bennin B, Gottlieb GJ. Histologic Diagnosis of Inflammatory Skin Diseases, 3rd Edition. New York: Ardor Scribendi, 2005.
Other works of ABA in which the ideas contrary are expressed:
1. Small Plaque Parapsoriasis (Guttate and Digitate Dermatosis) is Mycosis Fungoides(video)., available at: www.derm101.com, 2005.
2. Ruiz-Ballon M, Ackerman AB. Small plaque parapsoriasis (digitate and guttate dermatosis): chronic superficial scaly dermatitis or mycosis fungoides? 19932003.
Dermatopathology: Practical & Conceptual
9(4), 2003.
3. Chen L, and Ackerman AB. Mycosis fungoides is a systemic disease
sui generis
.
Dermatopathology: Practical & Conceptual
7(3):300-304, 2001.
4. Paichitrojjana A, Ackerman AB. Mycosis fungoides in historical perspective: a unifying concept.
Dermatopathology: Practical & Conceptual
7(3):279-295, 2001.
5. Papakonstantinou A, Ackerman AB. Brocq's graphic of parapsoriasis: interpretation through illustrations of his student, Achille Civatte.
Dermatopathology: Practical & Conceptual
6(3): 257-264, 2000.
6. Ackerman AB, Joshi RS, Resnik KS. Simplifying parapsoriasis.
Dermatopathology: Practical & Conceptual
4(3):209-11, 1998.
7. Hilbrich D, Ackerman AB. Mycosis fungoides is common, rarely fatal, and diagnosable when lesions are flat.
Dermatopathology: Practical & Conceptual
3(1):24-37, 1997.
8. Alapati U, Ackerman AB. An atlas of signs for histopathologic diagnosis of patch/plaque lesions of mycosis fungoides.
Dermatopathology: Practical & Conceptual
2(1):53-54, 1996.
9. Ackerman AB, Schiff TA. If small plaque (digitate) parapsoriasis is a cutaneous T-cell lymphoma, even an "abortive" one, it must be mycosis fungoides.
Arch Dermatol.
132(May):562-566, 1996.
10. DiLeonardo M, Ackerman AB. Small plaque parapsoriasis vs. chronic superficial scaly dermatitis vs. mycosis fungoides (small flat lesions).
Dermatopathology: Practical & Conceptual
2(3):178-179, 1996.
11. King-Ismael D, Ackerman AB. Guttate parapsoriasis/digitate dermatosis (small plaque parapsoriasis) is mycosis fungoides.
Am J Dermatopathol.
1992 Dec;14(6):518-30; discussion 531-535.
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