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Dermatopathology: Practical & Conceptual January - March 2006
>
5. New Heights: An assist to the next (10th) edition of “Lever’s”
Renata A. Joffe, M.D.
Content
Introduction
1. Small plaque parapsoriasis
2. Dysplastic nevus
3. Solar keratosis
4. Inverted follicular keratosis/trichilemmoma
5. Discoid lupus erythematosus vs. systemic lupus erythematosus
6. Lentigo maligna
7. Atopic dermatitis
8. Sebaceous adenoma
9. Muir-Torre syndrome
10. Bowen’s disease
11. Follicular mucinosis/alopecia mucinosa
12. Granuloma faciale and erythema elevatum diutinum
13. Follicular degeneration syndrome
14. Eccrine papillary adenoma
15. Degos’ disease
16. Dermatofibroma
17. Proliferating tricholemmal cyst
18. Erythema multiforme (dermal and epidermal types)
19. Lichen sclerosus et atrophicus vs. morphea
20. Malignant melanoma (classification)
21. Malignant melanoma—ABCD’s
22. Malignant melanoma—wide/deep excision
23. Sentinel node biopsy for melanoma
24. Malignant melanoma: nontumorigenic compartment of primary malignant melanoma (radial growth phase), tumorigenic compartment of primary malignant melanoma (vertical growth phase)
25. Minimal deviation melanoma
26. Nevoid melanoma
27. Malignant melanoma—in infancy and childhood
28. Malignant blue nevus
29. MELTUMP and SAMPUS
30. Bulge activation hypothesis
Conclusion
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12. Granuloma faciale and erythema elevatum diutinum
Quotation from the 9th edition of Lever's:
"Granuloma faciale may also resemble EED but is distinguished by clinical localization to the face, sparing of the superficial papillary dermis ( a 'grenz zone'), and prominence of eosinophils and plasma cells in addition to neutrophils"
"Granuloma faciale can appear similar to erythema elevatum diutinum, although a grenz zone and prevalence of eosinophils and plasma cells favors granuloma faciale"
Reference in the 9th edition to concepts contrary by A. Bernard Ackerman et al. (ABA): None.
Statements contrary by ABA:
"Error: Granuloma faciale and erythema elevatum diutinum are independent inflammatory processes and distinct from leukocytoclastic vasculitis. Reason: The "two" are nothing other than the same long-standing expression of leukocytoclastic vasculitis, the former given that name when lesions of it occur on the face and the latter assigned that appellation when lesions of it appear on the extensor aspects of extremities, especially of young women."
Ackerman AB, Böer A, Bennin B, Gottlieb GJ. Histologic Diagnosis of Inflammatory Skin Diseases, 3rd Edition. New York: Ardor Scribendi, 2005. (www.derm101.com)
Other works of ABA in which the ideas contrary are expressed:
1. Ackerman AB.
A Philosophy of Practice of Surgical Pathology: Dermatopathology as Model.
Philadelphia: Ardor Scribendi, 1999.
2. Ackerman AB. Chongchitnant N, Sanchez J, Guo Y.
Histologic Diagnosis of Inflammatory Skin Diseases.
2nd edition. Baltimore: Lippincott Williams & Wilkins, 1997.
3. Ackerman AB.
Histologic Diagnosis of Inflammatory Skin Diseases: A Method by Pattern Analysis.
Philadelphia: Lea and Febiger, 1978.
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