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Dermatopathology: Practical & Conceptual January - March 2006
>
5. New Heights: An assist to the next (10th) edition of “Lever’s”
Renata A. Joffe, M.D.
Content
Introduction
1. Small plaque parapsoriasis
2. Dysplastic nevus
3. Solar keratosis
4. Inverted follicular keratosis/trichilemmoma
5. Discoid lupus erythematosus vs. systemic lupus erythematosus
6. Lentigo maligna
7. Atopic dermatitis
8. Sebaceous adenoma
9. Muir-Torre syndrome
10. Bowen’s disease
11. Follicular mucinosis/alopecia mucinosa
12. Granuloma faciale and erythema elevatum diutinum
13. Follicular degeneration syndrome
14. Eccrine papillary adenoma
15. Degos’ disease
16. Dermatofibroma
17. Proliferating tricholemmal cyst
18. Erythema multiforme (dermal and epidermal types)
19. Lichen sclerosus et atrophicus vs. morphea
20. Malignant melanoma (classification)
21. Malignant melanoma—ABCD’s
22. Malignant melanoma—wide/deep excision
23. Sentinel node biopsy for melanoma
24. Malignant melanoma: nontumorigenic compartment of primary malignant melanoma (radial growth phase), tumorigenic compartment of primary malignant melanoma (vertical growth phase)
25. Minimal deviation melanoma
26. Nevoid melanoma
27. Malignant melanoma—in infancy and childhood
28. Malignant blue nevus
29. MELTUMP and SAMPUS
30. Bulge activation hypothesis
Conclusion
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13. Follicular degeneration syndrome
Quotation from the 9th edition of Lever's:
"Controversy exists regarding the concept of FDS as a distinct entity. Headington did not consider it so, noting that premature desquamation of the inner root sheath, considered the pathognomonic histologic finding, was not specific for FDS and could be seen in chronic cutaneous lupus erythematosus and pseudopelade of Brocq. Others have also equated this disorder with pseudopelade of Brocq, or classified it under the rubric of central centrifugal scarring alopecia."
"Although the precise etiology is unknown, hair care practices that include heat, bleaching, pomades and traction, as well as the predominance in African Americans, suggest that environmental, cultural, and genetic factors, as well as possible structural factors unique to hair follicle in blacks, may play a role in the etiology of FDS."
Reference in the 9th edition to concepts contrary by A. Bernard Ackerman et al. (ABA): None.
Statements contrary by ABA:
"Error: Follicular degeneration syndrome is an authentic disease of the inner sheath. Reason: Follicular degeneration syndrome is wholly without authenticity; the vast majority of patients said to have that syndrome actually have traction alopecia and, moreover, no disease of the inner sheath, which proponents of the 'syndrome' claim to have degenerated, ever has been identified."
Ackerman AB, Böer A, Bennin B, Gottlieb GJ. Histologic Diagnosis of Inflammatory Skin Diseases, 3rd Edition. New York: Ardor Scribendi, 2005. (www.derm101.com)
Other works of ABA in which the ideas contrary are expressed:
1. Charissi C, Ackerman AB. Traction alopecia in African women and in descendants of them: a critique in historical perspective.
Dermatopathology: Practical & Conceptual
9(4), 2003.
2. Ackerman AB, Mones J.
Resolving Quandaries in Dermatology, Pathology and Dermatopathology.
Vol 2 pp 171 New York: Ardor Scribendi, 2001.
3. Ackerman AB, Walton NW, Jones RE, Charissi C. Hot comb alopecia"/"follicular degeneration syndrome" in African-American women is traction alopecia!
Dermatopathology: Practical & Conceptual
6(4):320-336, 2000.
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