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Dermatopathology: Practical & Conceptual January - March 2006
>
5. New Heights: An assist to the next (10th) edition of “Lever’s”
Renata A. Joffe, M.D.
Content
Introduction
1. Small plaque parapsoriasis
2. Dysplastic nevus
3. Solar keratosis
4. Inverted follicular keratosis/trichilemmoma
5. Discoid lupus erythematosus vs. systemic lupus erythematosus
6. Lentigo maligna
7. Atopic dermatitis
8. Sebaceous adenoma
9. Muir-Torre syndrome
10. Bowen’s disease
11. Follicular mucinosis/alopecia mucinosa
12. Granuloma faciale and erythema elevatum diutinum
13. Follicular degeneration syndrome
14. Eccrine papillary adenoma
15. Degos’ disease
16. Dermatofibroma
17. Proliferating tricholemmal cyst
18. Erythema multiforme (dermal and epidermal types)
19. Lichen sclerosus et atrophicus vs. morphea
20. Malignant melanoma (classification)
21. Malignant melanoma—ABCD’s
22. Malignant melanoma—wide/deep excision
23. Sentinel node biopsy for melanoma
24. Malignant melanoma: nontumorigenic compartment of primary malignant melanoma (radial growth phase), tumorigenic compartment of primary malignant melanoma (vertical growth phase)
25. Minimal deviation melanoma
26. Nevoid melanoma
27. Malignant melanoma—in infancy and childhood
28. Malignant blue nevus
29. MELTUMP and SAMPUS
30. Bulge activation hypothesis
Conclusion
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26. Nevoid melanoma
Quotation from the 9th edition of Lever's:
"Although related to minimal deviation melanoma, this term has been used somewhat differently. Nevoid melanomas have been defined as lesions that, to a greater or lesser extent, mimic a benign nevus histologically, often with an emphasis on a nevoid architecture (in contrast to a minimal deviation melanoma, where melanoma architecture tends to be preserved)."
Reference in the 9th edition to concepts contrary by A. Bernard Ackerman et al. (ABA): None.
Statements contrary by ABA:
" For more than two decades, histopathologists have resorted to a variety of circumlocutions in their attempts to avoid acknowledging their inability to diagnose some melanocytic neoplasms with specificity. Chief among these are the terms borderline melanoma; minimal-deviation melanoma; atypical melanocytic neoplasm; and melanocytic neoplasm with architectural disorder, cytologic atypia or moderate dysplasia. None of these phrases qualify as definitive; all are dodges of specific diagnosis. The same is true for nevoid melanoma! Xif the diagnosis is melanoma, it should be rendered directly as melanoma and not be vitiated as nevoid melanoma that at best is ill conceived and at worst badly muddled."
Ackerman AB, Mones J.
Resolving Quandaries in Dermatology, Pathology and Dermatopathology.
pp 268-273. New York: Ardor Scribendi, 2001.
Other works of ABA in which the ideas contrary are expressed:
1. Ackerman AB. Mythology and numerology in the sphere of melanoma.
Cancer
88(3):491-496, 2000.
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