Illustrations

 
Figs. 1–3 show examples of "Clark nevus," "superficial congenital nevus," or "superficial and 'deep' congenital nevi." Figs. 4–10 very few of them truly being Clark's nevi (Fig. 11) actually show changes of a Clark's nevus.

View Figure  		Fig. 4  Comment: This is a superficial congenital nevus. (Reproduced from Greene WH, Fraumeni JF Jr. Human Malignant Melanoma. New York: Grune Stratton, Inc., 1979.)

View Figure  		Fig. 5  Comment: This is a superficial congenital nevus. (Elder DE, Greene MH, Bondi EE, et al. Acquired melanocytic nevi and melanoma. In: Ackerman AB (ed). Pathology of Malignant Melanoma. New York. Masson, 1981.)

View Figure  		Fig. 6  Comment: This is a superficial congenital nevus. (Reproduced from Clark WH Jr, Elder DE 4th, et al. A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma. Hum Pathol 1984;15(15):1147-65.)

View Figure  		Fig. 7  Comment: This is a superficial congenital nevus. (Reproduced from: Clark WH Jr, Ackerman AB. An exchange of views regarding the dysplastic nevus controversy. Seminars in Dermatology 1989;8(4):229-50.)

View Figure  		Fig. 8  Comment: This is likely a superficial congenital nevus. (Reproduced from Clark WH Jr, Ackerman AB. An exchange of views regarding the dysplastic nevus controversy. Seminars in Dermatology 1989;8(4):229-50.

View Figure  		Fig. 9  Comment: This is a superficial congenital nevus. (Reproduced from Pizzichetta MA, Masone C, Grandi G, et al. Morphologic changes of acquired melanocytic nevi with eccentric foci of hyperpigmentation ("Bolognia sign") assessed by dermoscopy. Arch Dermatol 2006;142:479-483.) Their figure legend: "Figure 2. One pigmented lesion from the trunk of a 5-year-old girl (original magnification 10 for panels A-D; 100 for panel E). A, The clinical image shows an eccentric focus of blue to black hyperpigmentation ("small dark dots") measuring 3 mm and localized in the lower half of the lesion. B, The first dermoscopic image shows a multicomponent pattern characterized by a homogeneous light brown pigmentation, irregular brown-black globules and dots, and an area of blue-gray pigmentation. C, The second dermoscopic image, taken 6 months later, shows a reduction in the number of irregular brown-black globules and dots and an increase of the blue-gray pigmentation. D, The third dermoscopic image, taken 9 months from the baseline evaluation, shows an increase in the number of atypical pigment network structures and a progressive increase in the blue-gray pigmentation. E, Histopathologic analysis reveals a compound dysplastic nevus with focal hyperpigmentation, nests of melanocytes in the epidermis and papillary dermis, and melanophages in the papillary dermis."

View Figure  		Fig. 10  Comment: This is a superficial congenital nevus. (Reproduced from Pizzichetta MA, Masone C, Grandi G, et al. Morphologic changes of acquired melanocytic nevi with eccentric foci of hyperpigmentation (" Bolognia sign") assessed by dermoscopy. Arch Dermatol 2006;142:479-483.) Their figure legend: "Figure 3. One pigmented lesion from the left thigh of a 5-year-old girl (original magnification X10 for panels A-C; X200 for panel D). A, The clinical image shows an eccentric focus of blue to black hyperpigmentation ("small dark dots") that measures 3 mm and is localized at the right periphery of the lesion. B, The first dermoscopic image shows homogeneous light brown pigmentation, regular light brown globules, and irregular dark dots localized at the right periphery of the lesion. In this area, blue-gray pigmentation can also be observed. C, The second dermoscopic image, taken 5 months later, shows a lesion with subtle changes: only a mild reduction of the blue-gray area and of the irregular dark dots. D, Histopathologic analysis reveals a compound dysplastic nevus with focal hyperpigmentation, nests of melanocytes in the epidermis and papillary dermis, and melanophages in the papillary dermis."

View Figure  		Fig. 11  Comment: These three lesions are Clark's nevi. Some photomicrographs published by Clark et al. actually show changes of a Clark's nevus. (Reproduced from Clark WH Jr, Elder DE 4th, et al. A study of tumor progression: The precursor lesions of superficial spreading and nodular melanoma. Hum Pathol 1984;15(15):1147-65.)