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< Current issue
Dermatopathology: Practical & Conceptual April - June 2008
>
4. General Pathology: What is the true nature of colonic adenoma? Part III: It is carcinoma
in situ—
a histopathology reassessment
Masoud Asgari, M.D.
Sheng Chen, M.D., Ph.D.
Introduction
Definition of terms
Histology of normal colonic mucosa
Histopathologic reassessment of so-called colonic adenoma
Discussion
Conclusion
Acknowledgement
Summary
References
SEE ALSO
-
colonic adenoma
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Definition of terms
Benign neoplasm:
A neoplasm with no capacity or potential for either destructive growth or metastasis.
Malignant neoplasm:
A neoplasm with capacity or potential for either destructive growth or metastasis.
Adenoma:
A benign neoplasm of glandular tissue or glandular epithelium.
Carcinoma:
A malignant epithelial neoplasm. Based on the presence or absence of stromal invasion, it can be categorized into either invasive carcinoma or carcinoma
in situ
. However, when the term carcinoma is used unmodified it generally refers to invasive carcinoma.
Carcinoma in situ:
A malignant epithelial neoplasm that is still confined in the epithelium of origin.
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