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< Current issue
Dermatopathology: Practical & Conceptual July - September 2008
>
10. New Heights: “Animal-type” melanoma and entities related to it. Part II: Devolution of the concept: animal-type melanoma, epithelioid blue nevus, pigmented epithelioid melanocytoma?
François Milette, M.D.
A. Bernard Ackerman, M.D.
Authors’ note
Introductory quotations
Contents of Part II
I. Pigmented epithelioid melanocytoma, animal-type melanoma, and epithelioid blue nevus (Zembowicz, Carney, and Mihm, 2004)
a. Epithelioid blue nevus in perspective historical
b. Epithelioid blue nevus (Carney and Ferreiro, 1996)
c. Presentation clinical of
pigmented epithelioid melanocytoma
d. Presentation histopathologic of
pigmented epithelioid melanocytoma
e. Concepts of
animal-type melanoma
and
epithelioid blue nevus in relation to pigmented epithelioid melanocytoma
f. Definition of terms ambiguous
g. Lack of legitimacy of any of the concepts set forth by Zembowicz, Carney, and Mihm
II. Pigmented epithelioid melanocytoma (Howard et al. 2005)
III. Equine/animal-type melanoma in humans: malignant melanoma with prominent pigment synthesis (Magro, Crowson, Mihm, 2006)
Afterword
Summary
References
SEE ALSO
-
animal-type melanoma
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g. Lack of legitimacy of any of the concepts set forth by Zembowicz, Carney, and Mihm
The authenticity of concepts promulgated in the article about "Pigmented epithelioid melanocytomas: a low-grade melanocytic tumor with metastatic potential indistinguishable from animal-type melanoma and epithelioid blue nevus" can be assessed best by posing questions in fashion Socratic:
1. Can you define
pigmented epithelioid melanocytoma
and list criteria for it, clinically and histopathologically?
2. Can you define
animal-type melanoma
and list criteria for it, clinically and histopathologically?
3. Can you define
epithelioid blue nevus of Carney complex
and list criteria for it, clinically and histopathologically?
4. Can you define
borderline melanocytic tumor
?
5. Given the fact that there is no such thing as
local metastasis
, metastasis by definition being disseminated, do you accept the premise that "pigmented epithelioid melanocytoma is a unique melanocytic neoplasm with low probability of systemic spread despite its ability to metastasize to regional lymph nodes"?
6. If a neoplasm composed of melanocytes metastasizes, do you think it is preferable to consider it a
pigmented epithelioid melanocytoma
rather than a melanoma?
7. Based on everything that has been presented here, which is representative truly of that written by Zembowicz, Carney, and Mihm, do you agree that " . . . it is best to consider pigmented epithelioid melanocytoma as a provisional histologic entity encompassing and synonymous with both animal-type melanoma and epithelioid blue nevus"?
If your answer to each of these seven questions is a resounding "No!," then you score 100% for capability to test reality as it is.
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