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Dermatopathology: Practical & Conceptual April - June 2003
Erratum: Proliferating Tricholemmal Cystic Carcinoma (Revision of Chapter XXV of the Volume Titled
Neoplasms with Follicular Differentiation,
2nd edition by Ackerman, Reddy, and Soyer, Ardor Scribendi, Ltd., 2001)
A. Bernard Ackerman M.D.
Joan Mones, D.O.
Stereotypical Example of a Proliferating Tricholemmal Cystic Acanthoma
Stereotypical Examples of Proliferating Tricholemmal Cystic Carcinomas
Cytopathologic Attributes of Proliferating Tricholemmal Cystic Carcinoma
Origin of Proliferating Tricholemmal Cystic Carcinoma
Differentiation of Proliferating Tricholemmal Cystic Carcinoma
Problems in Diagnosis of Proliferating Tricholemmal Cystic Carcinoma
Histopathologic Differential Diagnosis
Suppositions about Pathogenesis
proliferating tricholemmal cystic carcinoma
What has for decades been called "proliferating tricholemmal cyst" is not a cyst but a carcinoma that begins in a pre-existing follicular cyst. Both the cyst and the carcinoma that develops in it show differentiation toward the outer sheath at the isthmus (which, morphologically, is indistinguishable from the outer sheath as it involutes at a stage in catagen). The history of the evolution in thinking about this muddled matter is told in such a way that the subject, at long last, becomes crystal clear.
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