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Dermatopathology: Practical & Conceptual April - June 2008
4. General Pathology: What is the true nature of colonic adenoma? Part III: It is carcinoma
a histopathology reassessment
Masoud Asgari, M.D.
Sheng Chen, M.D., Ph.D.
Definition of terms
Histology of normal colonic mucosa
Histopathologic reassessment of so-called colonic adenoma
The subject of so-called colonic adenoma or adenomatous polyp is very controversial, confusing, and its real nature remains a mystery to date, as we have discussed previously in our review of the literature both historical and contemporary. [
In the present study we approach this issue via histopathologic reassessment of tissue sections of so-called colonic adenomas obtained from colonoscopic biopsies or surgical colectomy specimens. Based on the histopathologic findings, we conclude that so-called colonic adenoma is not adenoma at all, but carcinoma
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