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As their names denote, herpes simplex is caused by a herpesvirus and cowpox (vaccinia) by a poxvirus. Both are DNA viruses that induce lesions in the skin that share many findings histopathologic, e.g., intraepidermal vesicles surrounded by ballooned keratocytes, reticular alteration, and signs of necrosis of what originally were steel-gray nuclei. Viral inclusions are harbored […]