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Necrobiosis lipoidica Necrobiotic xanthogranuloma 1. Infiltrates of inflammatory cells equally dense throughout the dermis or “top-heavy” 1. Infiltrates of inflammatory cells “bottom-heavy” 2. Septal panniculitis with slight extension into lobules; architecture of the subcutaneous fat is preserved 2. Architecture of subcutaneous fat obliterated by extensive lobular and septal panniculitis 3. Upper part of the reticular […]