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Syringocystadenoma papilliferum Hidradenoma papilliferum 1. Not truly cystic (not a sac enclosed by epithelium) 1. Truly cystic (a sac enclosed completely or almost completely by epithelium) 2. Surface of skin papillated and hyperkeratotic 2. Surface of skin domed; cornified layer normal 3. Surface of lesion covered by three types of epithelium: epidermal, follicular, and apocrine […]