Please log in using your Derm101 Email/Username and Password to access the site.

Click here to Login | Subscribe to Derm101 Today!

Page Excerpt:

Introduction The desmogleins are a family of cadherins cell-cell adhesion molecules consisting of proteins DSG1, DSG2, DSG3, and DSG4. They play a role in the formation of desmosomes, which form the major types of intercellular adhesive junctions. DSGs are currently thought to be involved in autoimmune diseases, infectious diseases, and inherited diseases. Patients with pemphigus, […]