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See Fig. 5.239 A-C. Figure 5.239 A-C. Patterns of vesiculation: intraepidermal, subepidermal, and intra- and subepidermal. “Blister” and “vesiculobullous” are terms generic for lesions of the skin that usually are elevated above the surface of it and are distinguished clinically by containing a clear watery liquid that is observed by conventional microscopy to be serum. […]