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Histiocytosis X Presentation stereotypical Age and sex Children, boys mostly, and also adults Distribution of lesions Localized or widespread Individual lesions Red papules, purpuric papules, erosions, and ulcers Course Protracted, if not treated; sometimes fatal Variations clinical Letterer-Siwe’s disease consists of reddish-brown or purpuric often slightly scaly papules and plaques on the scalp, face, trunk, […]