Resolving Quandaries in Dermatology, Pathology & Dermatopathology


…that of necrotic cells. What, then, justifies the notion that apoptosis is not necrosis? Proponents of apoptosis as a type of cell death different from necrosis claim that in necrosis a nucleus explodes, whereas in apoptosis a nucleus implodes. Some…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

APOPTOSIS [Gk. apo- (away from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is claimed…

Histologic Diagnosis of Inflammatory Skin Diseases

Errors and Reasons

…t also of some collagen, is responsible for anetoderma. Error: Apoptosis is not necrosis. Reason: In classic Virchowian pathology, necrosis is characterized cytopathologically by three signs, namely, pyknosis, karyorrhexis, and karyolysis; apoptosis

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

See Figs. 5.16 A&B, 5.17 A&B, 5.18 A&B, 5.19 A&B, 5.20 A&B, 5.21 A&B, and 5.22 A&B Figure 5.16 A. Perivascular dermatitis, perivascular only, superficial. B. Perivascular dermatitis, perivascular only, superficial and…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

ABSCESS [L. abscessus (a going away)]: Clinically, a circumscribed collection of pus and histopathologically a localized collection of neutrophils. An abscess may form in the epidermis, both surface and infundibular, eccrine ducts, dermis, and subcu…