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Therapeutic Strategies in Dermatology

Extramammary Paget’s/Paget’s Disease: Overview

…the cutaneous lesion is identified involving the nipple of the breast, while extramammary Paget’s is used when the skin lesion is identified in an anogenital location. First Steps Evaluate the patient for an underlying carcinoma of the breast

A Clinical Atlas of 101 Common Skin Diseases

Mammary Paget’s

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…

Therapeutic Strategies in Dermatology

Acne Vulgaris: Treatment

Mild to moderate acne First-line therapy (comedonal acne only): topical retinoid First-line therapy (mild inflammatory acne): topical retinoid alone, topical retinoid + topical antimicrobial Topical retinoids are considered first line treat…

Therapeutic Strategies in Dermatology

Acrodermatitis Enteropathica: Overview

…in infants (hereditary or acquired) or adults (acquired). Some breastfed infants, especially if born prematurely, may develop acrodermatitis enteropathica due to zinc deficiency in mother’s breast milk. These children improve when given standar…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Breast a Sweat Gland?

“The breast is a modified sweat gland covered by skin and subcutaneous tissue.” Rosai J. The breast. In: Ackerman’s Surgical Pathology. 7th ed. St. Louis, MO: CV Mosby, 1989:1193. “The mammary glands are modified swat gla…

Differential Diagnosis in Dermatopathology

Metastatic carcinoma from a breast vs. Morpheiform basal-cell carcinoma

Mammary Paget’s disease is an apocrine carcinoma that begins in mammary glands and extends along lactiferous ducts to the epidermis where it is seen clinically as a scaly, crusted, or eroded plaque on the nipple or areola of women mostly, and…

A Clinical Atlas of 101 Common Skin Diseases

Extramammary Paget’s Disease and Mammary Paget’s Disease

Extramammary Paget’s disease is an apocrine carcinoma that begins within the epidermis and presents itself clinically as a patch or a subtle plaque that extends centrifugally for many years before becoming a readily discernible thick plaque, a…

Therapeutic Strategies in Dermatology

Scabies: Principles of Management of Scabies

Principles of Management of Scabies Initial therapy First line: Topical 5% permethrin cream, applied overnight to entire body except face, hair-bearing scalp. Rinse thoroughly and follow decontamination protocol. Treat patient and all household mem…

A Clinical Atlas of 101 Common Skin Diseases

Melanoma

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

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