Search Results for: fibrocytes

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Histologic Diagnosis of Inflammatory Skin Diseases

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…! It is an inflammatory process. Paradoxically, dermatofibrosarcoma protuberans, which is a true sarcoma, is affiliated with fibrocytes whose nuclei show no signs of atypia whatsoever, they being thin and wavy. 10.20.23A: Fibrosing dermatitis and…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…s formed by histiocytes in response to other foreign bodies such as tattoos, sutures, splinters, and mouth parts of insects. Fibrocytes Fibrocytes are cells that produce the fibers of fibrous and elastic tissue, and the ground substance of…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…htly eosinophilic, homogeneous-appearing collagen bundles disposed randomly and affiliated with an increased number of plump fibrocytes that parallel the long axis of the thickened bundles. A dermatofibroma is another type of fibrosis in which…

Histologic Diagnosis of Inflammatory Skin Diseases

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…ar, fully developed Plump fibrocytes are components of scars at a relatively early stage in the course of them, whereas thin fibrocytes are constituents of scars at a much later stage. The fibrocytes pictured here are intermediate between plump and…

Histologic Diagnosis of Inflammatory Skin Diseases

Nephrogenic fibrosing dermopathy

…a very early stage of that disorder and not always then, it being typified throughout its course by an increase in number of fibrocytes; fibrocytes in nephrogenic fibrosing dermopathy are increased markedly in number. Eosinophilic fasciitis is…

Histologic Diagnosis of Inflammatory Skin Diseases

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…owded, thickened bundles of collagen there as is the case in morphea) and by the presence of an increased number of abnormal fibrocytes (rather than a decreased number of seemingly normal ones as in morphea). 10.92.3A: Fibrosing dermatitis and…

Histologic Diagnosis of Inflammatory Skin Diseases

Radiation dermatitis and panniculitis

…and, sometimes, in septa in the subcutaneous fat, chronic radiodermatitis is accompanied by an increased number of peculiar fibrocytes marked by abnormal nuclei and abundant, often stellate-shaped cytoplasm. Some fibrocytes are binucleate. Other…

Histologic Diagnosis of Inflammatory Skin Diseases

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…nd in abundance. 10.54.3A: Fibrosing dermatitis + 10.54.3B: Markedly thickened bundles of collagen in random array and plump fibrocytes aligned along the long axis of those bundles = Keloid In time, fibrocytes in a keloid become thin and mucin in…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Sclerotic Fibroma?

…parallel bundles arranged in striking storiform pattern.” Three of the lesions were hypocellular with scant, elongated fibrocytes positioned as solitary units among bundles of collagen, whereas the other lesion showed a proliferation of plump…

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