Search Results for: histiocytes

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Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…ed with plasma cells are syphilis, rhinoscleroma, and granuloma inguinale, but the actual number of such diseases is legion. Histiocytes Histiocytes are tissue macrophages that originate as promonocytes in the bone marrow, whence, within a few…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…hematoxylin and eosin. 10.43.14A: Perivascular and interstitial dermatitis + 10.43.14B: Lymphocytes around blood vessels and histiocytes between collagen bundles = Granuloma annulare The infiltrate in the interstitium consists of histiocytes, just…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…tion with Infiltrates of Inflammatory Cells Abundant mucin in the reticular dermis in association with either lymphocytes or histiocytes or both. Click image to enlarge. In foci: + Histiocytes in palisaded or interstitial array in discrete foci =…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…anulomas of tuberculoid leprosy, whereas foamy histiocytes monopolize in granulomas of lepromatous leprosy; both epithelioid histiocytes and foamy histiocytes are present together in granulomas of dimorphous leprosy. Foamy histiocytes, known also as…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…phocytes in collections of epithelioid and slightly foamy histiocytes = Leprosy, borderline The presence of both epithelioid histiocytes and slightly foamy histiocytes makes this lesion “borderline,” i.e., between the tuberculoid and…

Histologic Diagnosis of Inflammatory Skin Diseases

Xanthogranuloma

histiocytes pleomorphic; most oval and monomorphous Some histiocytes in mitosis Fully developed Dense diffuse infiltrate of histiocytes Many histiocytes with foamy cytoplasm Some histiocytes Touton in type; many of them sometimes Infiltrate of…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ance in granuloma annulare in which lymphocytes are dominant. 10.67.4A: Perivascular and interstitial dermatitis + 10.67.4B: Histiocytes, some multinucleate, in patchy distribution along vascular plexuses = Necrobiosis lipoidica The infiltrate of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…ks. Sections of tissue from biopsy specimens showed numerous eosinophils, some of them clustered as flame figures, and large histiocytes, some of them multinucleate, arranged in a palisade around flame figures. In the third and last stage, the…

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