Search Results for: hypergranulosis

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A Clinical Atlas of 101 Common Skin Diseases

Alopecias

Loss of hair attributable either to the effects of inflammatory cells on follicles or to physiological or mechanical factors in which inflammatory cells play no role. Although the scalp is the site most often affected, any region of the skin that be…

A Clinical Atlas of 101 Common Skin Diseases

Verrucae

Papules on skin and mucous membranes that result from infection of keratinocytes by different types of papillomavirus and classified according to their silhouettes, to wit, papillated (verrucae vulgares on different sites such as volar skin, i.e., v…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…rmal junction by lymphocytes, jagged acanthosis, wedge-shaped hypergranulosis, and compact orthokeratosis = Lichen planus, early Zones of wedge-shaped hypergranulosis are centered around acrosyringia and the upper part of infundibula. 10.60.2A: Periv…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen planus

…idual necrotic keratocytes Jagged acanthosis and wedge-shaped hypergranulosis Cornified layer mostly basket-weave, but compact orthokeratosis especially above foci of hypergranulosis Fully developed Superficial perivascular infiltrate of lymphocytes…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…vascular dermatitis, psoriasiform + 10.23.1B: Orthokeratosis, hypergranulosis, acanthosis, proliferation of infundibular and eccrine ductal keratocytes, and coarse bundles of collagen in vertical streaks = Lichen simplex chronicus (“epidermal a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…e extensive solar elastosis, absence of wedge-shaped zones of hypergranulosis in repeatable fashion, and foci of basket-weave arrangement of corneocytes in the stratum corneum. So-called lichen planus-like keratosis simply is a stage in devolution of…

Histologic Diagnosis of Inflammatory Skin Diseases

Applicable Terms

…Those conditions are typified also by compact orthokeratosis, hypergranulosis, acanthosis, and proliferation of infundibular, and sometimes eccrine ductal, keratocytes. Distinctive changes of lichen simplex chronicus may be produced in pruritic skin…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…the dermoepidermal interface, a few necrotic keratocytes, and hypergranulosis in a thin epidermis = Graft-versus-host disease The differential diagnoses of this example of graft-versus-host disease are “eruption of lymphocytic recovery” (…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…slight focal parakeratosis beneath a normal cornified layer, hypergranulosis, thin epidermis nearly devoid of rete ridges, and lymphocytes along the dermoepidermal interface = Graft-versus-host disease/eruption of lymphocyte recovery + Wedge-shaped…

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