Search Results for: lymphocytes

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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Persistent Lentiginous Melanocytic Hyperplasia, Atypical Melanocytic Hyperplasia (Melanocytic Nuclear Atypia), Lamellar Fibroplasia, Concentric Fibroplasia, and Lymphocytes as Criteria for Diagnosis Histopathologic of Dysplastic Nevi?

…erentiating Clark’s nevus from melanoma. Infiltrates of lymphocytes do not aid in distinguishing nevi of any kind from melanomas. Dense infiltrates of them are seen in halo nevi and often in Spitz’s nevi, as well as in many melanomas. Lym…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Perivascular Dermatitis

…present themselves, at a minimum, with infiltrates made up of lymphocytes positioned around venules of the superficial plexus. When viewed at scanning power, a perivascular dermatitis is identified by the presence of inflammatory cells around venules…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…completion of an algorithm successfuly are recorded. Abnormal Lymphocytes in a Mixed-Cell Infiltrate of Inflammatory Cells Lymphocytes with large pleomorphic nuclei in the epidermis, dermis, or subcutaneous fat or at a combination of those sites; syn…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…: Perivascular dermatosis, psoriasiform lichenoid + 11.14.1B: Lymphocytes, sparse in both the dermis and epidermis, larger in the epidermis than in dermis, solitary in the basal layer in foci, and in association with scant spongiosis in the spinous z…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…sis fungoides associated with lymphadenopathy and circulating lymphocytes whose nucleus is abnormal in its cerebriform convolution. Differential diagnosis clinical Psoriasis usually is distributed symmetrically on extensor surface, especially as plaq…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Nodular and Diffuse Dermatitis

…ously in regard to a “bottom heavy” infiltrate of lymphocytes of a perivascular “dermatitis,” especially one that also affects the subcutaneous fat, a nodular “dermatitis” of lymphocytes that is distinctly “b…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

Neutrophils, eosinophils, lymphocytes, plasma cells, and histiocytes are called inflammatory cells because they enter tissue during the process of inflammation. A more exact designation for them is “cells of an inflammatory process”; the…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

….2A: Perivascular dermatitis, interface, vacuolar + 10.63.2B: Lymphocytes around venules and along the dermoepidermal junction = Lupus erythematosus, discoid  A surfeit of mucin in the lower part of the reticular dermis is expected in many expression…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…interstitial dermatosis, infundibulocentric + 11.13.1B: Small lymphocytes, large abnormal lymphocytes, neutrophils and eosinophils = Lymphomatoid papulosis  Episodically, as shown here, an infiltrate of lymphomatoid papulosis is distributed mostly in…

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