Search Results for: lymphocytes

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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Persistent Lentiginous Melanocytic Hyperplasia, Atypical Melanocytic Hyperplasia (Melanocytic Nuclear Atypia), Lamellar Fibroplasia, Concentric Fibroplasia, and Lymphocytes as Criteria for Diagnosis Histopathologic of Dysplastic Nevi?

…om melanomas. Dense infiltrates of them are seen in halo nevi and often in Spitz’s nevi, as well as in many melanomas. Lymphocytes are not always present in dysplastic nevi, and when they are present tend to be sparse. Unfortunately for…

Histologic Diagnosis of Inflammatory Skin Diseases

Algorithms Predicated on “Nonspecific” Findings

…ical lymphocytes, and some lymphocytes often in mitosis = Lymphomatoid papulosis + Nodular or diffuse infiltrate of abnormal lymphocytes; lymphocytes often in the epidermis, sometimes in collections there = Mycosis fungoides    …

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…14.29A: Perivascular dermatosis, patchy lichenoid + 11.14.29B: Wiry bundles of collagen in foci of lichenoid infiltration of lymphocytes, lymphocytes as solitary units in a spinous zone with scant spongiosis, and elongated mounds of parakeratosis =…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…e dermal papillae stuffed by lymphocytes Wiry bundles of collagen arranged haphazardly in zones of lichenoid infiltration of lymphocytes Lymphocytes with nuclei having a cerebriform outline Eosinophils present in variable number Epidermis sometimes…

Histologic Diagnosis of Inflammatory Skin Diseases

Cells That Mediate Inflammation (Inflammatory Cells)

…equence in diagnosis histopathologic of inflammatory skin diseases as that is set forth in the method advanced in this book. Lymphocytes Lymphocytes begin life in the bone marrow as lymphoblasts and there mature into prolymphocytes. Once in the…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…mis and the subcutaneous fat. 10.63.12A: Perivascular dermatitis and panniculitis, lobular + 10.63.12B: Patchy infiltrate of lymphocytes and nuclear “dust” of lymphocytes in association with sclerosis = Lupus erythematosus, discoid,…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…may be monomorphous, as is the situation here, or polymorphous, with all kinds of inflammatory cells in addition to abnormal lymphocytes. When lymphocytes are rivetingly abnormal as in this instance, it is highly likely that manifestations of…

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