A Clinical Atlas of 101 Common Skin Diseases

Squamous-Cell Carcinoma

A malignant neoplasm of keratinocytes that when present as a keratotic macule or papule on skin damaged badly by sunlight is referred to as solar keratosis. When present as a plaque it is termed Bowen’s disease, and when present as many papule…

A Clinical Atlas of 101 Common Skin Diseases

Epidermal Nevi

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Differential Diagnosis in Dermatopathology

Discussions

…cleroderma. Systemic sclerosis may be fatal; morphea never is. Scleredema (known also as scleredema adultorum of Buschke) affects young adults. About 50 percent of patients present themselves to a physician at an age younger than 20 years. There is n…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

Epidermal nevi are hamartomas in which the epidermis is abnormal, being hyperkeratotic, and in which lesions are aligned along Blaschko’s lines….

Differential Diagnosis in Dermatopathology

Discussions

…ases whose names begin with “scler-“: scleroderma, scleredema, scleromyxedema, and sclerema. The latter three diseases are not related in any way to the “sclerodermas.” Scleredema adultorum of Buschke is not an inflammatory di…

Differential Diagnosis in Dermatopathology

Study By Disease

…#542) Scabies (Quiz #543) Schamberg’s disease (Quiz #44) Scleredema adultorum (Buschke) (Quiz #40) Sebaceous carcinomas in a patient with Muir-Torre syndrome (Quiz #72) Sebaceous nevus (not nevus sebaceus of Jadassohn) (Quiz #444) Seborrheic de…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiotic xanthogranuloma

…y to dermatofibrosarcoma protuberans or sclerema neonatorum to scleredema adultorum), the two diseases have in common, besides names that sound somewhat alike, palisaded granulomas in the dermis and the subcutaneous fat with degeneration of collagen…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Scleroderma (morphea) Scleredema (Buschke) 1. Dermis thickened slightly 1. Dermis thickened markedly, sometimes three or more times normal 2. Collagen bundles thickened markedly 2. Collagen bundles thickened only slightly 3. Collagen bundles…

Differential Diagnosis in Dermatopathology

Images

Scleroderma (morphea) Scleredema (Buschke)…