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A Clinical Atlas of 101 Common Skin Diseases

Deep Fungal Infections

Cutaneous and subcutaneous lesions, usually nodules, that have become keratotic, crusted, and ulcerated as a consequence of infection by a variety of deep fungi, i.e., fungi situated in the dermis and subcutis, some of which may be disseminated to o…

A Clinical Atlas of 101 Common Skin Diseases

Tuberculosis

An inflammatory process caused by Mycobacterium tuberculosis. In the skin, it may be primary as a consequence of direct inoculation (tuberculosis verrucosa cutis) or secondary to a focus of tuberculosis in another organ (the lung for lupus vulgaris,…

A Clinical Atlas of 101 Common Skin Diseases

Acne Vulgaris

A disease of infundibulosebaceous units, especially infundibula, that may manifest itself solely as noninflammatory lesions, i.e., comedones and intact cysts, or as inflammatory lesions, i.e., papules, nodules, and pustules. The process may resolve…

A Clinical Atlas of 101 Common Skin Diseases

Nodular Vasculitis

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

A Clinical Atlas of 101 Common Skin Diseases

Pyoderma Gangrenosum

An inflammatory process that often begins as a suppurative folliculitis manifested clinically as pustules. It rapidly extends to become ulcers marked at their periphery by boggy tissue. The skin disease is associated commonly with inflammatory bowel…

A Clinical Atlas of 101 Common Skin Diseases

Atypical Mycobacterial Infections

Infection of skin and subcutaneous tissue by atypical mycobacteria, that is, mycobacteria other than those responsible for tuberculosis and leprosy, expressed clinically as keratotic and crusted papules, plaques, nodules, and tumors that may be punc…

Histologic Diagnosis of Inflammatory Skin Diseases

Atypical mycobacterial infections

…uperficial and deep perivascular mixed-cell infiltrate Foci of suppuration in the dermis and often in infundibula Fully developed Suppuration in the dermis and sometimes in lobules in the subcutaneous fat Necrosis of adipocytes in lobules varies fr…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.37.1A: Pustular dermatitis, infundibular + 10.37.1B: Numerous Demodex folliculorum and squames in a zone of suppuration = Suppurative infundibulitis of unknown cause Demodex, Pityrosporum, bacteria, sebum, squames, and cornified…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

See Fig. 5.307 A&B. Figure 5.307 Pustular dermatitis. A. Infundibular. B. Surface epidermal. Although most pustules in skin are housed in infundibular epidermis (Fig. 5.308 A&B), many are lodged in surface epidermis (Fig. 5.309 A&B)….

Histologic Diagnosis of Inflammatory Skin Diseases

Nodular vasculitis

…s fat necrosis present also in lobules in the subcutaneous fat Suppuration met with in foci in lobules Granulomatous inflammation distributed near loci of fat necrosis and of suppuration in fat lobules Granulation tissue and fibrosis in patchy array…

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