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Histologic Diagnosis of Inflammatory Skin Diseases

Grover’s disease

…not focal and does not show acantholytic dyskeratotic cells, acanthosis, or parakeratosis; infundibular epidermis and epithelial structures of adnexa tend to be involved in the same manner as surface epidermis. Pemphigus foliaceus when expressed ful…

Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

…lentiginous nevus. The biopsy was taken from the thigh. Mild acanthosis and hyperpigmentation of basal keratinocytes is present but there is no marked proliferation of melanocytes. Figures 6A-G. Histopathology of the ulcerated melanoma arising in…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…is in infundibular, as well as surface, epidermis 7. Slight acanthosis of rete ridges of even length and breadth; some suprapapillary plates may be thin 7. Slight acanthosis rete ridges of uneven length and breadth; suprapapillary plates not thin…

Dermatology Practical & Conceptual

Human papillomavirus-induced periungual pigmented Bowen’s disease

…rated a pigmented Bowen’s disease (Figure 3). There was acanthosis with focal hypergranulosis and parakeratosis. The epidermis was composed of atypical keratinocytes and few scattered dyskeratotic cells. The superficial dermis had a light periv…

Histologic Diagnosis of Inflammatory Skin Diseases

Lichen striatus

…ome multinucleate histiocytes present in the papillary dermis Acanthosis, sometimes psoriasiform Necrotic keratocytes disposed as individual units and often in clusters near the base of the epidermis; sometimes those cells present in the papillary de…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…presence of a stratum corneum still normal and the absence of acanthosis. 10.50.3A: Perivascular dermatitis, psoriasiform lichenoid + 10.50.3B: Lymphocytes and many eosinophils in association with numerous individual necrotic keratocytes =…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…cally never contained wholly in a 4.0 mm biopsy specimen 2. Acanthosis and hyperpigmentation usually; epidermis sometimes thinned in the center of the lesion 2. No acanthosis or hyperpigmentation; entire surface epidermis often thinned 3. Inducti…

Dermatology Practical & Conceptual

From the Dermatologikum Hamburg

…ed in Figures 2A-P shows irregular epidermal and infundibular acanthosis and dilation of infundibula filled with neutrophils. Diffuse infiltrates are present in the dermis and are dominated by far by neutrophils. Some nuclear dust of neutrophils is p…

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