Search Results for: alpha-1 antitrypsin deficiency

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Histologic Diagnosis of Inflammatory Skin Diseases

Images

…arakeratosis. As long as the original cornified layer covers mounds of parakeratosis, no scale can be appreciated clinically. 10.90.2A: Perivascular dermatitis, psoriasiform + 10.90.2B: Neutrophils in elongated mounds of parakeratosis in tiers…

Histologic Diagnosis of Inflammatory Skin Diseases

Dermatomyositis

…d with a malignant neoplastic process housed in an internal organ. Dermatomyositis has been affiliated, too, with hereditary deficiency of C2, with thymoma, and with treatment by penicillamine. Comment Some lesions of indisputable dermatomyositis…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Anagen Effluvium?

…ecessary to begin with Crounse and his coworkers, who, in an article published in the Journal of Investigative Dermatology in 1960 (Crounse RG, Van Scott EJ, Changes in scalp hair roots as a measure of toxicity, Cancer Chemotherapeutic Drugs…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atopic Dermatitis?

…y. In: Cotran RS, Kumar V, Collins T, eds. Robbins Pathologic Basis of Disease, 6th ed. Philadelphia: W. B. Saunders Company, 1999: 199. “Atopic dermatitis (atopic eczema) is a chronic, pruritic, inflammatory disease of the skin which usually…

Histologic Diagnosis of Inflammatory Skin Diseases

Advantages of the Algorithmic Method

…ptophan-myalgia syndrome) and progressive systemic sclerosis (acrosclerosis, diffuse systemic sclerosis, toxic oil syndrome) Deficiency diseases (including pellagra, acrodermatitis enteropathica, necrolytic migratory erythema, Hartnup’s…

Histologic Diagnosis of Inflammatory Skin Diseases

Limitations of the Algorithmic Method

…realistically, “lymphocytic vasculitis” has no place. Because one criterion for inclusion of diseases in Chapter 10 is that they be definable both clinically and histopathologically, lymphocytic vasculitis does not qualify. The method…

Histologic Diagnosis of Inflammatory Skin Diseases

Syphilis

…rch Dermatol 1973;107:373-77. Jordaan HF, Louw M. The moth-eaten alopecia of secondary syphilis. A histopathological study of 12 patients. Am J Dermatopathol 1995;17:158-62. McBroom RL, Styles AR, Chiu MJ, et al. Secondary syphilis in persons…

Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

…hronica, parapsoriasis guttata, parapsoriasis en plaques, and parapsoriasis variegata. Since Brocq’s seminal article in 1902 devoted exclusively to parapsoriasis, those five conditions have been held to be vaguely related to one another in a…

From the Dermatologikum Hamburg: Quiz

From the Dermatologikum Hamburg: Quiz

…peared thickened (Figure 1B). There were multiple, small hypopigmented scars on the chest, dorsa of hands, and cheeks (Figure 1C). Figure 1A. Erythematous lesions on the forearm, some with crusts. Figure 1B. Thickening of skin over knuckles and…

Histologic Diagnosis of Inflammatory Skin Diseases

Necrobiotic xanthogranuloma

…2003;108:274-80. Finan MC, Winkelmann RK. Histopathology of necrobiotic xanthogranuloma with paraproteinemia. J Cutan Pathol 1987;14:92–99. Georgiou S, Monastirli A, Kapranos N, et al. Interferon alpha-2a monotherapy for necrobiotic…

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