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Differential Diagnosis in Dermatopathology


…hite zone becomes more indurated before resolving with subtle atrophy and hyperpigmentation known then as the idiopathic atrophoderma of Pasini and Pierini. Morphea profundus is not the only expression of morphea to involve subcutaneous tissue. Anoth…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

…idermis and of adnexal epithelium in the center of the lesion Atrophy progressively of the epidermis Late Wedge-shaped zone of sclerosis throughout the dermis, the apex of the wedge pointing towards the subcutaneous fat Mucin discernible, especiall…

Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus foliaceus

…er further by development, in time, of pigmentary changes and atrophy. Bullous lupus erythematosus is associated with tense blisters. Miscue clinical as clue to diagnosis histopathologic Pemphigus erythematosus may be misdiagnosed clinically as lup…

Dermatology Practical & Conceptual

A verrucous plaque on the lower leg

…verrucous plaque with an elevated border and central areas of atrophy and scar formation. The patient was otherwise healthy, in an excellent physical profile (Figure 1). He had no associated leg pain, abdominal pain, or any history of recurrent fever…

Histologic Diagnosis of Inflammatory Skin Diseases

Post-inflammatory pigmentary alteration

…inflammatory pigmentary change is a category generic, akin to atrophy, poikiloderma, lipodystrophy, scar, and keloid, each of those conditions being recognizable for what they are clinically, having certain distinguishing characteristics histopatholo…

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