Search Results for: atrophy

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Histologic Diagnosis of Inflammatory Skin Diseases

Pemphigus foliaceus

…higus erythematosus, but they are devoid of blisters. They differ further by development, in time, of pigmentary changes and atrophy. Bullous lupus erythematosus is associated with tense blisters. Miscue clinical as clue to diagnosis histopathologic…

A verrucous plaque on the lower leg

A verrucous plaque on the lower leg

…nvolving the entire lower leg. Clinical examination revealed a verrucous plaque with an elevated border and central areas of atrophy and scar formation. The patient was otherwise healthy, in an excellent physical profile (Figure 1). He had no…

An itching plaque

An itching plaque

…s or biopsy [3]. Biopsy samples show a polymorphous infiltrate with plasma cells and variable epidermal response (acanthosis/atrophy/ulceration). While late lesions show well organized, tuberculoid granulomas, early lesions show spread macrophages…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

…but also of eosinophils Necrosis, in variable degree, of the epidermis and of adnexal epithelium in the center of the lesion Atrophy progressively of the epidermis Late Wedge-shaped zone of sclerosis throughout the dermis, the apex of the wedge…

Differential Diagnosis in Dermatopathology

Necrobiosis lipoidica vs. Necrobiotic xanthogranuloma

A disease of infundibulosebaceous units, especially infundibula, that may manifest itself solely as noninflammatory lesions, i.e., comedones and intact cysts, or as inflammatory lesions, i.e., papules, nodules, and pustules. The process may resolve…

Differential Diagnosis in Dermatopathology

Discussions

…e infiltrate of inflammatory cells lessens, but the yellow or white zone becomes more indurated before resolving with subtle atrophy and hyperpigmentation known then as the idiopathic atrophoderma of Pasini and Pierini. Morphea profundus is not the…

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