Differential Diagnosis in Dermatopathology

Discussions

…to the porokeratotic type under discussion here. Each of these singular changes represents a distinctive epithelial pattern morphologic that is encountered also in settings different from epidermal nevi, e.g., focal acantholytic dyskeratosis in Grove…

Clinical Case Studies

Nevus of Ota

…, HHL, Kono, T. Nevus of Ota: Clinical Aspects and Management. SKINmed 2003. 2:89–98. 14673306 2. Lui, H, Zhou, Y. Nevi of Ota and Ito. 2004. http://www.emedicine.com/DERM/topic290.htm 3. Watanabe, S, Takahashi, H. Treatment of Nevus of Ota with the…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Invasion by Neoplastic Cells?

…ubcutaneous fat), as invasive, but neoplastic melanocytes of a Spitz nevus positioned in the dermis or subcutaneous fat, as well as in the epidermis, never are designated invasive (even though neoplastic melanocytes of some Spitz nevi grow much faste…

Differential Diagnosis in Dermatopathology

Discussions

…ormal in number or decreased. When fibrocytes are increased in such a nevus, they may assume various shapes, e.g., oval, spindle, and dendritic, and they may be multinucleate. A remarkable feature of nuclei of fibrocytes in some collagenous nevi is t…

Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

…tiation, but also in juvenile xanthogranuloma or granulomatous skin diseases [1]. It is more surprising that recent dermatoscopic observations report on yellow color in both melanocytic nevi and melanoma [2,3]. Herein we would like to add an addition…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…, Hintner-Wolff): Onset at birth, blisters widespread, lesions sometimes heal with atrophy and scarring; onycholysis, cicatricial alopecia, extracutaneous involvement episodical; large melanocytic nevi, course clinical is of progressive improvement o…