Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Metastasizing Dermatofibroma?

…“benign” tumors with rare metastasis which include such examples as uterine leiomyomas and salivary mixed tumor.” Colome-Grimmer MI, Evans HL. Metastasizing cellular dermatofibroma: a report of two cases. Am J Surg Pathol 1996;20:13…

Dermatology Practical & Conceptual

Glomangiosarcoma in the shoulder of a 51-year-old man

…myeloma and another with thyroid cancer. Physical examination showed an overweight middle aged male with multiple small freckles, skin tags and nevi over his trunk and neck. A 1 cm pink, firm, rubbery, non-tender nodule was present on the back of le…

Differential Diagnosis in Dermatopathology

Morphea, late stage vs. Collagenous nevus

A malignant neoplasm of melanocytes that, in the skin, begins as a macule and may become a patch or a papule. A flat lesion of melanoma tends to be asymmetrical, poorly circumscribed with a scalloped, jagged, or notched border, and variegate, mostly…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…, Hintner-Wolff): Onset at birth, blisters widespread, lesions sometimes heal with atrophy and scarring; onycholysis, cicatricial alopecia, extracutaneous involvement episodical; large melanocytic nevi, course clinical is of progressive improvement o…

Differential Diagnosis in Dermatopathology

Discussions

…ormal in number or decreased. When fibrocytes are increased in such a nevus, they may assume various shapes, e.g., oval, spindle, and dendritic, and they may be multinucleate. A remarkable feature of nuclei of fibrocytes in some collagenous nevi is t…

Clinical Case Studies

Nevus of Ota

…, HHL, Kono, T. Nevus of Ota: Clinical Aspects and Management. SKINmed 2003. 2:89–98. 14673306 2. Lui, H, Zhou, Y. Nevi of Ota and Ito. 2004. http://www.emedicine.com/DERM/topic290.htm 3. Watanabe, S, Takahashi, H. Treatment of Nevus of Ota with the…

Dermatology Practical & Conceptual

Yellow color upon dermatoscopy does not exclude melanoma!

…tiation, but also in juvenile xanthogranuloma or granulomatous skin diseases [1]. It is more surprising that recent dermatoscopic observations report on yellow color in both melanocytic nevi and melanoma [2,3]. Herein we would like to add an addition…