Search Results for: collagen

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Differential Diagnosis in Dermatopathology

Differential Diagnosis

…ckened slightly 1. Dermis thickened markedly, sometimes three or more times normal 2. Collagen bundles thickened markedly 2. Collagen bundles thickened only slightly 3. Collagen bundles packed; spaces between them narrow 3. Collagen bundles not…

Histologic Diagnosis of Inflammatory Skin Diseases

Degos’ disease (malignant atrophic papulosis)

…21; diseaseOcclusion of vessels in the lower half of the reticular dermis leads to infarction and subsequent degeneration of collagen, intraepidermal vesiculation, and epidermal necrosis. In time, degeneration of collagen is replaced by sclerosis,…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…grin, and generalized atrophic benign junctional epidermolysis bullosa with antibodies against bullous pemphigoid antigen 2 (collagen type XVII). Findings by electron microscopy are these: Junctional epidermolysis bullosa (Herlitz): Cleavage in the…

Histologic Diagnosis of Inflammatory Skin Diseases

"Folliculitis" (Infundibulitis)

…are detailed in subchapters in this work devoted to each of them Differential diagnosis histopathologic Reactive perforating collagenosis does not involve infundibula Elastosis perforans serpiginosa is marked by strikingly altered eosinophilic…

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