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Histologic Diagnosis of Inflammatory Skin Diseases

Images

…dermatitis and panniculitis + 10.48.1B: Thick bundles of collagen in haphazard array replace much of the subcutaneous fat and a marked increase in number of thick-walled vessels in the upper part of the dermis = Hypodermitis sclerodermiformis  T…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…Numerous oval fibrocytes, histiocytes, and coarse bundles of collagen arranged haphazardly; interlacing fascicles episodically 4. Numerous oval, spindled, and wavy cells in company with fibrillary bundles of collagen arranged often in short interlac…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…e-shaped fibrocytes in conjunction with fibrillary bundles of collagen, abundant mucin, scattered lymphocytes, and extravasated erythrocytes = Nodular fasciitis  This condition fundamentally is fibrosing granulation tissue that occurs in response to…

Histologic Diagnosis of Inflammatory Skin Diseases

Junctional epidermolysis bullosa

…conventional microscopy. Laboratory confirmation Staining for collagen IV and keratin immunoperoxidase reveals the former to lie on the floor of the blister and the latter to reside on the undersurface of the roof of the blister. The use of monoclona…

Histologic Diagnosis of Inflammatory Skin Diseases

"Folliculitis" (Infundibulitis)

…is, but a foreign body reaction to hair. Reactive perforating collagenosis is a consequence of severe trauma external that causes ulceration and degeneration of collagen bundles; it is not an infundibular or a follicular process, but a factitious one…

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