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Histologic Diagnosis of Inflammatory Skin Diseases

Elastosis perforans serpiginosa

…ltered elastic fibers across a front in the upper part of the dermis Channels of epithelium through the epidermis house orthokeratotic and parakeratotic cells, neutrophils and nuclear debris of neutrophils, and red-staining elastic fibers that are th…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…with dull, amphophilic, homogeneous globules in the papillary dermis + 11.3.1C + 11.3.1D = Amyloidosis, macular  The absence of any sign of lichen simplex chronicus indicates that this is a macular, rather than a papular, expression of a…

Histologic Diagnosis of Inflammatory Skin Diseases

Hypodermitis sclerodermiformis

…lymphocytes around venules in the lower half of the reticular dermis and in the subcutaneous fat Marked increase in number of thickened capillaries and venules lined by plump endothelial cells in the upper half of the dermis, i.e., evidences of sever…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…ed by any changes at the dermoepidermal junction or in the epidermis. It is a description, not a diagnosis. Diseases characterized by infiltrates of lymphocytes around both superficial and deep vascular plexuses in the dermis include polymorphous lig…

Histologic Diagnosis of Inflammatory Skin Diseases

Persistent light reaction

…nophils; some lymphocytes may be larger than normal Papillary dermis thickened also by coarse bundles of collagen disposed in vertical streaks Plump, stellate, and multinucleate fibrocytes in the thickened papillary dermis Acanthosis, sometimes uneve…

Histologic Diagnosis of Inflammatory Skin Diseases

Pyoderma gangrenosum

…ndibular epithelium in and around an abscess in the reticular dermis, a sign of rupture of an infundibulum stuffed with neutrophils Subcorneal pustule, if present, representing the uppermost part of a suppurative infundibulitis, the infundibulum havi…

Histologic Diagnosis of Inflammatory Skin Diseases

Elastic Fibers

…ell as branching (Fig. 1.81). Elastic fibers in the papillary dermis are present either as bundles of microfibrils, oxytalan fibers, or as cross-linked elastin on one hand or as elaunin fibers on the other. In the reticular dermis, elastic tissue app…

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