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Histologic Diagnosis of Inflammatory Skin Diseases

Persistent light reaction

…inophils; some lymphocytes may be larger than normal Papillary dermis thickened also by coarse bundles of collagen disposed in vertical streaks Plump, stellate, and multinucleate fibrocytes in the thickened papillary dermis Acanthosis, sometimes unev…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lymphocytic Infiltration of Jessner?

…other lymphocytic infiltrates by marked edema of the papillary dermis and the tumid form of discoid lupus erythematosus can be identified for what it is by the presence of abundant mucin in the reticular dermis. Erythema figuratum cannot be different…

Histologic Diagnosis of Inflammatory Skin Diseases

Hypodermitis sclerodermiformis

…lymphocytes around venules in the lower half of the reticular dermis and in the subcutaneous fat Marked increase in number of thickened capillaries and venules lined by plump endothelial cells in the upper half of the dermis, i.e., evidences of seve…

Histologic Diagnosis of Inflammatory Skin Diseases

Pyoderma gangrenosum

…nse diffuse infiltrate of neutrophils extending throughout the dermis and, sometimes, into the subcutaneous fat Remnant of infundibular epithelium sometimes detected in the large abscess Edema of the papillary dermis sometimes becoming subepidermal v…

Histologic Diagnosis of Inflammatory Skin Diseases

Elastic Fibers

…well as branching (Fig. 1.81). Elastic fibers in the papillary dermis are present either as bundles of microfibrils, oxytalan fibers, or as cross-linked elastin on one hand or as elaunin fibers on the other. In the reticular dermis, elastic tissue ap…

Histologic Diagnosis of Inflammatory Skin Diseases

Prurigo pigmentosa

…le comes into being mostly by virtue of edema in the papillary dermis, but also because of an infiltrate of inflammatory cells in the dermis and the epidermis; a papulovesicle consists of elements of an urticarial papule with the addition of spongios…

Dermatology Practical & Conceptual

Melanoma and satellite blue papule

…collagen bundles, correlating to solar elastosis at the upper dermis (Figure 4). HD-OCT (Skintell┬«, AgfaHealthCare, Belgium) en face mode enabled the observation of scattered bright inflammatory cells in the dermis and clusters of bright coarse part…

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