Clinical Case Studies

Progressive Ascending Telangiectasia

…NTATION A 49-year-old white female presented with widespread diffuse blue vessels on her lower extremities. The vessels appeared suddenly, 16 years after the birth of her third child. The vessels started on the feet and ankles, and progressed proxim…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine, Apocrine, and Apoeccrine Sweat Glands?

…oeccrine sweat gland. This type of gland shows a segmental or diffuse apocrinelike dilatation of its secretory tubule but has a long and thin duct, which does not open into a hair follicle. The electron microscopy of its distal segment is often indis…

Histologic Diagnosis of Inflammatory Skin Diseases

Erysipelas

…onous inflammation, a response characterized by a sparse, but diffuse, infiltration by neutrophils in the reticular dermis and, sometimes, the subcutaneous fat. Erysipelas is the stereotype of cellulitis. When search is undertaken for streptococci re…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Common Baldness—an Inflammatory Disease?

…s seen in 75% of patients and focal fibrosis was seen in 25%. Diffuse dermal fibrosis with destruction of follicular structures was present in 5% of the scalp biopsy samples. This degree and severity of inflammatory damage was an unexpected finding a…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.36.1A: Diffuse dermatitis, mixed-cell, and pseudocarcinomatous proliferation of keratocytes + 10.36.1B: Amphophilic ovoid bodies in the cytoplasm of infundibular keratocytes = Milker’s nodule Changes identical with these a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eczema?

…ered over Erythematous skin. Often the scaling is so fine and diffuse that the skin acquires a silvery sheen. Chronic eczema is characterized by thickened skin and increased skin markings, called lichenification, secondary to rubbing and scratching&#…