Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.36.1A: Diffuse dermatitis, mixed-cell, and pseudocarcinomatous proliferation of keratocytes + 10.36.1B: Amphophilic ovoid bodies in the cytoplasm of infundibular keratocytes = Milker’s nodule Changes identical with these a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Follicular Degeneration Syndrome?

“An irreversible alopecia of the scalp occurs in negro women who straighten their hair with hot combs. The disease is common and distinctive, clinically and histopathologically. . . . Hot petrolatum used with the comb causes a chronic inflamm…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eccrine, Apocrine, and Apoeccrine Sweat Glands?

“Evidence is presented that in adult human axillae there exists a third type of sweat gland tentatively designated as the apoeccrine sweat gland. This type of gland shows a segmental or diffuse apocrinelike dilatation of its secretory tubule…

Histologic Diagnosis of Inflammatory Skin Diseases

Erysipelas

Erysipelas Synonyms St. Anthony’s fire Ignis sacer Erysipele Erysipela Presentation stereotypical Age and sex Any age and either sex, but with a predilection for older persons with diabetes, peripheral vascular disease, and abuse of alcohol…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Common Baldness—an Inflammatory Disease?

“The results also show that inflammation in MPA [male pattern alopecia] is a relatively consistent finding and that, although often insignificant, this frequently leads to an inflammatory folliculitis, perifollicular fibrosis, and unusually…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Endothelial Swelling?

“In PLEVA, the more severe form, one observes vascular changes consisting of a pronounced mononuclear infiltrate around capillaries, with the capillaries showing endothelial swelling and permeation of their walls by the infiltrate. This usua…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eczema?

“Eczema is that which looks like eczema.” Hebra F. Kaposi M. Lehrbuch der Hautkrankheiten. Bd, 2. Aufl. Erlangen: Enke, 1874:403-93. “In Anglo-American usage, the term dermatitis is being used increasingly for all these conditi…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

See Fig. 5.307 A&B. Figure 5.307 Pustular dermatitis. A. Infundibular. B. Surface epidermal. Although most pustules in skin are housed in infundibular epidermis (Fig. 5.308 A&B), many are lodged in surface epidermis (Fig. 5.309 A&B)….