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Histologic Diagnosis of Inflammatory Skin Diseases

Images

…d in spongiotic foci of a slightly acanthotic, hyperkeratotic epidermis, erythrocytes being extravasated in both the dermis and the epidermis. = Pityriasis rosea, early ┬áMounds of parakeratosis in pityriasis rosea usually are positioned near spongiot…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…aepidermal blister having exploded. All of the changes in the epidermis are secondary to infarction consequent to the effects of changes in the wall of venules, to wit, deposits of fibrin in it. Figure 5.232 A&B. An ulcer covered by crust in l…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus Versus Systemic Lupus Erythematosus?* I

…d sometimes along the dermoepidermal junction and even in the epidermis. Mucin may be increased in quantity in the reticular dermis. In time, classic discoid lupus erythematosus consists of a superficial and deep perivascular infiltrate of lymphocyte…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal and Epidermal Types of Erythema Multiforme?

…f those blisters tends to become gray as a consequence of the epidermis having undergone necrosis. In his atlas of dermatopathology published in the 1950s, Achilles Civatte pictured erythema multiforme histopathologically as a lesion with an epidermi…

Histologic Diagnosis of Inflammatory Skin Diseases

Fox-Fordyce disease

…nfundibula by orthokeratotic cells Acanthosis of infundibular epidermis Spongiosis of infundibular epidermis, including spongiotic vesiculate. Cornoid lamellation in infundibula sometimes Ballooning and vacuolar alteration, and individual dyskeratoti…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…nction, slight spongiosis, and necrotic keratocytes in a thin epidermis = Graft-versus-host disease Sometimes it is difficult to differentiate graft-versus-host disease from erythema multiforme on grounds histopathologic alone, but the distinction ca…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo?

…irely different proliferations of melanocytes confined to the epidermis (and to the uppermost part of epithelial structures of the adnexa). One of those conditions consists of a slight increase in the number of monomorphic melanocytes disposed as sol…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ictured resulted from rupture of one housed originally in the epidermis. A dense infiltrate of lymphocytes in the dermis is a finding expected in some lesions caused by herpesvirus. Many of the lymphocytes have large pleomorphic nuclei. 10.47.7…

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