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Differential Diagnosis in Dermatopathology

Discussions

The interstitial expression of granuloma annulare and of papular mucinosis have several findings histopathologic in common, among them mesenchymal cells with abundant pink cytoplasm scattered among bundles of collagen, multinucleate cells in section…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.78.1A: Perivascular and interstitial dermatitis, lymphocytic + 10.78.1B: Numerous extravasated erythrocytes in conjunction with a monomorphous population of lymphocytes = Schamberg’s disease, early ┬áThis is but one of seve…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Pseudopelade?

“In October, 1888, we presented a review of folliculitis and perifolliculitis decalvans at the Soci?t? m?dicale des h?pitaux, and, at this moment, we have nothing to add; there are three principal clinical types related in some way to one ano…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma faciale

Granuloma faciale Presentation stereotypical Age and sex Adults of both sexes Distribution of lesions Localized to the face Shape of lesions Round or oval usually Individual lesions Papules, plaques, nodules, or tumors marked on their surface often…

Histologic Diagnosis of Inflammatory Skin Diseases

Kimura’s disease

Kimura’s disease Synonyms Eosinophilic lymphofolliculitis Presentation stereotypical Age and sex Young men, especially Asians Distribution of lesions Head, neck, and trunk Individual lesions Firm nodules and tumors, some gigantic, above which…

Histologic Diagnosis of Inflammatory Skin Diseases

Leprosy

Leprosy Synonyms Hansen’s disease Lepra Presentation stereotypical Age and sex Young adults of both sexes who live in endemic areas Distribution of lesions Localized in indeterminate and tuberculoid types; widespread and symmetrical in lepro…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum leprosum

Erythema nodosum leprosum Features clinical Red nodules or plaques that may develop anywhere but especially the thighs and legs Findings histopathologic Early Suppurative lobular panniculitis, focal at first and then diffuse Patchy zones of extensi…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.58.1A: Perivascular and interstitial dermatitis + 10.58.1B: Neutrophils and copious quantities of nuclear “dust” of neutrophils in association with many extravasated erythrocytes = Leukocytoclastic vasculitis, early…

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