Search Results for: histiocytes

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Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum

…. Another challenge in diagnosis is posed by sarcoidosis when it is composed of “naked” tubercles of epithelioid histiocytes that are dispersed throughout lobules, as well as housed in fibrous septa, a combination of findings that…

Histologic Diagnosis of Inflammatory Skin Diseases

Fox-Fordyce disease

…alteration, and dyskeratotic cells may be encountered there. In the dermis, an infiltrate composed of a few lymphocytes and histiocytes may surround infundibular and apocrine ductal epithelium. Sometimes histiocytes take on a xanthomatous aspect by…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

…reticular dermis Lymphocytes distributed sparsely around venules of the superficial and, sometimes, deep plexus Epithelioid histiocytes, sometimes multinucleate, may accompany lymphocytes in the interstitium Changes of mycosis fungoides in surface…

Histologic Diagnosis of Inflammatory Skin Diseases

Leishmaniasis

…dermis and, at times, involving the septa of the subcutaneous fat Numerous gray-blue dots of Leishmania in the cytoplasm of histiocytes Edema in the upper part of the dermis often Ulceration sometimes Chronic cutaneous Fully developed Tuberculoid…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…process. 10.56.2A: Perivascular and interstitial dermatitis, interface, lichenoid + 10.56.2B: Lymphocytes, plasma cells, and histiocytes that contain tiny round monomorphous basophilic organisms = Leishmaniasis, acute The distinctive character of…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…a granulomatous panniculitis (and sometimes dermatitis) in which huge deposits of fibrin are surrounded by thin epithelioid histiocytes arrayed in a palisade. From the preceding brief descriptions, it is apparent that striking histopathologic…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Wegener’s Granulomatosis?

…venules, and arterioles. The vasculitis was said to be “necrotizing granulomatous” and to consist of epithelioid histiocytes and histiocytic giant cells within the wall of vessels, often in company with variable numbers of lymphocytes…

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