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Histologic Diagnosis of Inflammatory Skin Diseases

Lichen striatus

…eticular dermis Patchy lichenoid infiltrate of lymphocytes and histiocytes obscuring the dermoepidermal junction and, sometimes, the junction between adnexal epithelium and the dermis Some multinucleate histiocytes present in the papillary dermis Aca…

Histologic Diagnosis of Inflammatory Skin Diseases

Fox-Fordyce disease

…In the dermis, an infiltrate composed of a few lymphocytes and histiocytes may surround infundibular and apocrine ductal epithelium. Sometimes histiocytes take on a xanthomatous aspect by virtue of ingestion of lipid-laden apocrine secretion that com…

Histologic Diagnosis of Inflammatory Skin Diseases

Leishmaniasis

Leishmaniasis Synonyms Leishmaniosis Presentation stereotypical Age and sex Young adults of both sexes Distribution of lesions Localized in Oriental sore, widespread in the mucocutaneous and post-kala-azar types, and disseminated in the anergic cuta…

Histologic Diagnosis of Inflammatory Skin Diseases

Mycosis fungoides

Mycosis fungoides Synonyms Cutaneous T-cell lymphoma Presentation stereotypical Age and Sex Adults usually, although children may be affected. Males preponderant. Distribution of lesions Often widespread, but sometimes localized to a single patch or…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…lichenoid + 10.56.2B: Lymphocytes, plasma cells, and histiocytes that contain tiny round monomorphous basophilic organisms = Leishmaniasis, acute The distinctive character of the organisms in the cytoplasm of histiocytes establishes the…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…mucin are abundant, in the center of palisades of epithelioid histiocytes. Rheumatoid nodule is a granulomatous panniculitis (and sometimes dermatitis) in which huge deposits of fibrin are surrounded by thin epithelioid histiocytes arrayed in a pali…

Differential Diagnosis in Dermatopathology

Discussions

…;stereotypical” examples of xanthogranuloma display some histiocytes with “ground glass” cytoplasm and, in reverse, some “stereotypical” examples of granuloma exhibit histiocytes with foamy cytoplasm. These findings are…

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