Search Results for: hypergranulosis

1 8 9 10
Large cell acanthoma: a debate throughout the decades

Large cell acanthoma: a debate throughout the decades

…skin, characterized by extraordinarily large cells with polyploidy [1]. LCA presents sharply demarcated hyperorthokeratosis, hypergranulosis, and enlarged keratinocytes without signs of atypical mitoses or nuclear dysplasia. Pinkus separated actinic…

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

…s of a verruca vulgaris, namely, acanthosis with elongated rete ridges bent toward the center of the lesion, papillomatosis, hypergranulosis with koilocytes, and compact orthokeratosis with narrow columns of parakeratosis above elongated papillae….

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…Leukokeratosis Leukoplakia 1. Orthokeratosis with few parakeratotic cells 1. Parakeratosis with few orthokeratotic cells 2. Hypergranulosis 2. Few, if any, granular cells in a lesion that has not been rubbed persistently 3. Epithelium thickened…

Diagnostic utility of Ki-67 and Cyclin D1 immunostaining in differentiation of psoriasis vs. other psoriasiform dermatitis

Diagnostic utility of Ki-67 and Cyclin D1 immunostaining in differentiation of psoriasis vs. other psoriasiform dermatitis

…dermal papillae [1]. The presence of thickened collagen bundles arranged in vertical streaks in the dermal papillae, marked hypergranulosis and a thick layer of compact orthokeratosis resembling that seen on normal palms and soles (i.e., hairy palm…

Pigmented Lesions

Pigmented Lesions

…orm, plasmacytoid, and polygonal. Pseudoacantholysis of melanocytes is common. Often there are compact orthokeratosis, focal hypergranulosis, adnexal hyperplasia, dull pink globules in the epidermis, and clefts between nests/fascicles of melanocytes…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…rthokeratosis in basket-woven and lamellate patterns 2. Thick epidermis, either papillated or digitated 2. Thin epidermis 3. Hypergranulosis usually 3. Granular zone normal or slightly decreased in thickness 4. Epidermis sometimes hyperpigmented 4….

Differential Diagnosis in Dermatopathology

Discussions

…perkeratosis and a plane wart share several findings histopathologic, among them being a papillated and thickened epidermis, hypergranulosis, and cells with pale cytoplasm within the epidermis. The terms “epidermolytic hyperkeratosis”…

1 8 9 10