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Differential Diagnosis in Dermatopathology

Discussions

Lichen planus and lichenoid discoid lupus erythematosus have many findings histopathologic in common, among them hyperkeratosis of surface epidermis and plugs of cornified cells in infundibular epidermis; individual necrotic keratocytes; a lichenoid…

Differential Diagnosis in Dermatopathology

See Classification of Pigmented Lesions

Non-melanocytic lesions Inflammatory Post-inflammatory hyperpigmentation Dermatofibroma Hamartomas Collagenous nevus, papillary dermal type Nevoid hyperkeratosis of the nipple Benign neoplasms Solar lentigo, including lichen planus-like ker…

Differential Diagnosis in Dermatopathology

Discussions

Changes histopathologic in both lupus erythematosus profundus and panniculitis-like T-cell lymphoma involve the subcutaneous fat especially where they have in common an infiltrate, in lobules and septa, comprised mostly of lymphocytes, fat necrosis…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Churg-Strauss Granuloma and Allergic Granulomatosis?

“The occurrence of a clinical syndrome of severe asthma, fever, and hypereosinophilia, together with symptoms of vascular embarrassment in various organ systems, has been established. . . . The basic anatomical changes . . . consisted of wide…

Differential Diagnosis in Dermatopathology

Discussions

Porokeratotic epidermal nevus and inflammatory linear verrucous epidermal nevus have in common well-circumscribed loci of parakeratosis beneath which the granular zone is absent, alternation of zones of ortho- and parakeratosis, and an epidermis tha…

Differential Diagnosis in Dermatopathology

Discussions

Perforating folliculitis and elastosis perforans serpiginosa have several findings histopathologic in common: an epithelial channel through surface epidermis; neutrophils in the channel; a collection of neutrophils contiguous with the channel; foci…

Differential Diagnosis in Dermatopathology

Pigmented Lesions

Non-melanocytic lesions Inflammatory Post-inflammatory hyperpigmentation¬†(523, 649) Melanophages in number variable scattered in the papillary dermis, rarely in the upper part of the reticular dermis too. Melanin increased in amount in the epi…

Differential Diagnosis in Dermatopathology

Discussions

Leukokeratosis and leukoplakia are white, slightly elevated nonindurated lesions of the mucosae (especially of the mouth, but also of the vagina and other areas) that also have some attributes histopathologic in common, namely, hyperkeratosis, a thi…

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