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Differential Diagnosis in Dermatopathology

Pale-cell acanthoma vs. Psoriasis, plaque expression

What prompted the undertaking of this pocket atlas of dermatology? The reasons were several and varied, among them the following: 1.  Pictures are and always have been an extraordinarily valuable vehicle in the study of clinical dermatology. The fir…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Lichen planus Lichen planus-like keratosis 1. Compact orthokeratosis; no parakeratosis usually 1. Orthokeratosis, often compact, and focal parakeratosis 2. Granular zone thickened focally and in wedge shape 2. Granular zone thickened and thinn…

Histologic Diagnosis of Inflammatory Skin Diseases

Fox-Fordyce disease

Fox-Fordyce disease Synonyms Apocrine miliaria Presentation stereotypical Age and sex Postpubertal women mostly Distribution of lesions Sites where apocrine glands are numerous, i.e., axillae, periumbilical, pubic, and areolae Arrangement of lesions…

Histologic Diagnosis of Inflammatory Skin Diseases

See Classification of Pigmented Lesions

…Benign neoplasms Solar lentigo, including lichen planus-like keratosis Seborrheic keratosis Malignant neoplasms Basal cell carcinoma, pigmented Solar keratosis, pigmented Melanocytic lesions Benign Melanosis Simple lentigo Nevus of Ota, ne…

Differential Diagnosis in Dermatopathology

Discussions

…r) mucinosis. When pale-cell acanthosis occurs in a seborrheic keratosis, for example, the lesion may simulate pale-cell acanthoma closely, but the seborrheic keratosis may be recognized for what it is by the presence of laminated hyperkeratosis, tun…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

Regression of lichen planus-like keratosis Regression of primary cutaneous melanoma 1. Signs of residual solar lentigo or reticulated seborrheic keratosis apparent in sections of tissue sometimes 1. No residual keratocytic neoplasm such as solar…

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