Search Results for: melanocytes

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Clinical Case Studies

Nevus of Ota

…ated incidence of 0.014–0.034% among Asians.1 Although the etiology and pathogenesis are unknown, Nevus of Ota may represent melanocytes that failed to completely migrate from the neural crest to the epidermis during the embryonic stage.2 The two…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

…. Fluid and Electrolyte Abnormalities in Exocrine Glands in Cystic Fibrosis. San Francisco: San Francisco Press, 1982:35-52. Melanocytes Boissy RE. The melanocyte. Its structure, function, and subpopulations in skin, eyes, and hair. Dermatol Clin…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Changing Mole?

…nge independently should be cause for alarm.” Rhodes AR. Neoplasms: benign neoplasias, hyperplasias, and dysplasias of melanocytes. In: Fitzpatrick TB, Eisen AZ, Wolff K, et al., eds., Dermatology in general medicine. 4th ed. New York:…

Reflectance confocal microscopy: a useful and non-invasive tool in the in vivo differentiation of benign pigmented skin lesions from malignant melanoma. Report of a case

Reflectance confocal microscopy: a useful and non-invasive tool in the in vivo differentiation of benign pigmented skin lesions from malignant melanoma. Report of a case

…showed epidermal hyperplasia characterized by thin strands of basaloid cells and basal hyperpigmentation without increase of melanocytes. In the superficial dermis, few melanophages and solar elastosis were present. [Copyright: ©2013…

Balloon cell melanoma in primary care practice: a case report

Balloon cell melanoma in primary care practice: a case report

…he second component, by contrast, was comprised of centrally positioned atypical aggregates of grossly distended epithelioid melanocytes, exhibiting a pseudo-xanthomatous balloon cell change in their cytoplasm, and pleomorphic vesicular nuclei with…

A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

…opathologic assessment (Figure 2 composite) showed a small, but asymmetric, nested and single cell proliferation of atypical melanocytes along the dermoepidermal junction with scattered single cell intraepithelial upward spread. There was limited…

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

…f superficial dermal melanophages is thought to be responsible for the bluish background (HE, x20). Pigmented spindle-shaped melanocytes predominate in well-demarcated junctional nests (insets, x100 and x200). [Copyright: ©2016 Pedrosa et al.]…

Histologic Diagnosis of Inflammatory Skin Diseases

Post-inflammatory pigmentary alteration

…in which inflammatory cells dislodged melanin from keratocytes in the basal layer of the epidermis especially, but also from melanocytes there, the melanin lost having been garnered by macrophages. Vacuolar alteration present still along the…

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

…d. (C, D) Specimen 2 shows the compound stage of a Clark’s nevus. The lesion is symmetrical and sharply circumscribed, melanocytes are distributed in regular fashion, and there are no melanocytes in the upper reaches of the epidermis. There is…

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