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Dermatology Practical & Conceptual

Large cell acanthoma: a debate throughout the decades

…canthoma showed statistically significant increased numbers of melanocytes compared with both normal skin and actinic keratosis. The number of melanocytes did not differ significantly between LCA and solar lentigo. In the era of dermoscopy, dermoscop…

Differential Diagnosis in Dermatopathology

Discussions

…ma in situ because some examples of that malignant neoplasm of melanocytes, especially those situated on the trunk and extremities, are characterized by abnormal pagetoid melanocytes distributed in pagetoid pattern in the epidermis and adnexal epithe…

Dermatology Practical & Conceptual

Melanoma and satellite blue papule

Abstract The colors that are seen in dermoscopy depend on the anatomic level of the skin at which the chromophores are seen. Blue color can be found in a variety of melanocytic and nonmelanocytic lesions. An 89-year-old man presented with a 3-year h…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal Papilla?

“Historically, the hair germ has been defined as a group of cells located at the base of the telogen follicle in close contact with the dermal papilla.” Lavker RM, Miller S, Wilson C, et al. Hair follicle stem cells: their location, ro…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…histiocytes); no polygonal cells 4. Polygonal cells (abnormal melanocytes), but also abnormal melanocytes of different shapes 5. Melanophages rare; siderophages and lipophages common 5. Melanophages common; no siderophages or lipophages 6. Lymph…

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