Search Results for: melanocytes

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A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

A tiny invasive melanoma: a case report with dermatoscopy and dermatopathology

…opathologic assessment (Figure 2 composite) showed a small, but asymmetric, nested and single cell proliferation of atypical melanocytes along the dermoepidermal junction with scattered single cell intraepithelial upward spread. There was limited…

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

Spitz/Reed nevi: a review of clinical-dermatoscopic and histological correlation

…f superficial dermal melanophages is thought to be responsible for the bluish background (HE, x20). Pigmented spindle-shaped melanocytes predominate in well-demarcated junctional nests (insets, x100 and x200). [Copyright: ©2016 Pedrosa et al.]…

Balloon cell melanoma in primary care practice: a case report

Balloon cell melanoma in primary care practice: a case report

…he second component, by contrast, was comprised of centrally positioned atypical aggregates of grossly distended epithelioid melanocytes, exhibiting a pseudo-xanthomatous balloon cell change in their cytoplasm, and pleomorphic vesicular nuclei with…

Histologic Diagnosis of Inflammatory Skin Diseases

Post-inflammatory pigmentary alteration

…in which inflammatory cells dislodged melanin from keratocytes in the basal layer of the epidermis especially, but also from melanocytes there, the melanin lost having been garnered by macrophages. Vacuolar alteration present still along the…

Melanoma and satellite blue papule

Melanoma and satellite blue papule

…microscopy examination (mosaic 2 x 2 mm): normal honeycomb pattern, edged-papillae, absence of atypical cells and dendritic melanocytes in the dermis; elongated cords and bulbous projections (yellow circle), flattened junction and moderately…

Differential Diagnosis in Dermatopathology

Discussions

…ust be differentiated histopathologically from pagetoid melanoma in situ because some examples of that malignant neoplasm of melanocytes, especially those situated on the trunk and extremities, are characterized by abnormal pagetoid melanocytes

Large cell acanthoma: a debate throughout the decades

Large cell acanthoma: a debate throughout the decades

…atistically significant increased numbers of melanocytes compared with both normal skin and actinic keratosis. The number of melanocytes did not differ significantly between LCA and solar lentigo. In the era of dermoscopy, dermoscopic features of a…

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

Confusion—specimen mix-up in dermatopathology and measures to prevent and detect it

…d. (C, D) Specimen 2 shows the compound stage of a Clark’s nevus. The lesion is symmetrical and sharply circumscribed, melanocytes are distributed in regular fashion, and there are no melanocytes in the upper reaches of the epidermis. There is…

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