1 8 9 10
Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

…come a vesiculopustule and then a pustule as a consequence of necrosis of keratocytes secondary to cytopathic effects of the virus, the necrotic epithelial cells being chemotactic for neutrophils, which enter the blister and convert it into a pustule…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…Sections from another biopsy specimen showed “fibrinoid necrosis,” deposits of eosinophilic granular material, and histiocytes around debris of eosinophils. Despite having presented the child as an example of Wells’ syndrome of auto…

Differential Diagnosis in Dermatopathology

Differential Diagnosis

…wall of small, medium-sized, and large vessels 7. Extensive necrosis en masse of adipocytes; karyorrhexis and karyolysis striking 7. Necrosis of adipocytes manifested mostly by karyorrhexis; karyolysis present, but subtle 8. Membanous fat necrosi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cytophagic Panniculitis?

…the subcutis, there may be locular [sic] panniculitis and fat necrosis, together with massive hyaline necrosis, oedema, and haemorrhage. Diagnosis In its later stages the condition is distinguished from malignant histiocytosis by its chronic course a…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dermal and Epidermal Types of Erythema Multiforme?

…ecome gray as a consequence of the epidermis having undergone necrosis. In his atlas of dermatopathology published in the 1950s, Achilles Civatte pictured erythema multiforme histopathologically as a lesion with an epidermis peppered by individual ne…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…ermis, marked ballooning, reticular alteration, and confluent necrosis of the roof of the original blister = Erythema multiforme The dynamic of erythema multiforme may be episodic, in contrast with psoriasis, in which the dynamic is periodic, and wit…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema multiforme

…lvement of the skin and mucous membranes is extensive. Severe necrosis of the epidermis results in large sheets that peel off in the manner of lesions in a second-degree burn. It may be life threatening because of loss of fluids from skin unprotected…

1 8 9 10