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Dermatology Practical & Conceptual

Melanoma arising in a giant nevus spilus maculosus

Abstract Melanoma arising in a nevus spilus is rare. There are two distinct types of nevus spilus characterized by macular or papular speckles, respectively. We report the case of a melanoma that arose in association with a giant nevus spilus maculo…

Dermatology Practical & Conceptual

Pigmented Lesions

Non-melanocytic lesions Inflammatory Post-inflammatory hyperpigmentationĀ (523, 649) Melanophages in number variable scattered in the papillary dermis, rarely in the upper part of the reticular dermis too. Melanin increased in amount in the epi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

“There has been a tendency in recent years to phase out the term ‘mycosis fungoides’ and replace it with peripheral cutaneous T-cell lymphoma (CTCL).” Santa Cruz DJ, Hurt MA. Neoplasms of the skin. In: Sternberg SS, ed. Dia…

Differential Diagnosis in Dermatopathology

Lymphocytoma cutis with lymphoid follicles vs. Follicular-cell lymphoma

A hamartoma of epidermis, epithelial structures of adnexa, and presumably dermal elements, typified, when fully formed, by a papillated or verrucous yellowish plaque situated usually on the scalp. The condition may present itself as a solitary lesio…

Differential Diagnosis in Dermatopathology

See Classification of Pigmented Lesions

…llary dermal type Nevoid hyperkeratosis of the nipple Benign neoplasms Solar lentigo, including lichen planus-like keratosis Seborrheic keratosis Malignant neoplasms Basal cell carcinoma, pigmented Solar keratosis, pigmented Melanocytic les…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dysplasia?

“Dysplasia (Ger.) n. A disturbance of formative activity.” Foster FP. Foster’s Encyclopedic Medical Dictionary. New York, NY: D. Appleton & Co., 1891:1378. “Dysplasia shares many cytologic features with cancer, and th…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Endothelial Swelling?

“In PLEVA, the more severe form, one observes vascular changes consisting of a pronounced mononuclear infiltrate around capillaries, with the capillaries showing endothelial swelling and permeation of their walls by the infiltrate. This usua…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

“This is a study of the clinical features of four patients in the light of particular cutaneous histopathology. The characteristic eruption is periodic, tending to recur every few months, usually without systemic symptoms. The acute state of…

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