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Differential Diagnosis in Dermatopathology


…itary reticulohistiocytic granuloma typically is a dome-shaped nodule positioned on a face or a scalp. Multicentric reticulohistiocytosis also consists of dome-shaped nodules, and they tend to affect the face and hands. Polyarthritis of variable seve…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

Granuloma annulare Presentation stereotypical Age and sex Any age in both sexes Distribution of lesions Localized, often to extensor aspects of extremities, or widespread Configuration of lesions Annular, sometimes arcuate Arrangement of lesions Sca…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Inverted Follicular Keratosis, Tricholemmoma, and Desmoplastic Tricholemmoma?

“For about the last 8 years my associates and I have been observing a lesion—a keratosis—which occurs mostly on the face: I should say about 90 percent on the face, the remainder on other parts of the body. These lesions are characterized cli…

Histologic Diagnosis of Inflammatory Skin Diseases

“Kyrle’s disease”

“Kyrle’s disease” Comment In our view, Kyrle’s disease is analogous in a way to Weber-Christian syndrome, Rothmann-Makai disease, Churg-Strauss allergic granulomatous, Wegener’s granulomatosis, Sulzberger-Gorbe disease,…

Histologic Diagnosis of Inflammatory Skin Diseases

Foreign body reaction

Foreign body reaction Synonyms Foreign body granuloma Presentation stereotypical Age and sex Any age and either sex Distribution of lesions Localized usually Individual lesions Papules, plaques, and nodules Course Longstanding Variations clinical…

Dermatology Practical & Conceptual

Pigmented tumor in the nostril

Abstract A 64-year-old man was noted to have a single pigmented lesion in the nostril of his nose. Clinical examination revealed a 5 mm nodular growth and brown lesion. With a presumed clinical diagnosis of malignant skin tumor, a biopsy was perform…

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