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Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

In 1963, the year that one of us (A.B.A.) began a residency in dermatology, Walter Lever’s textbook, Histopathology of the Skin, was in its third edition and was deemed, universally, to be “the bible” of dermatopathology. To a firs…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus Versus Systemic Lupus Erythematosus?* I

*This subject was addressed in Resolving Quandaries I. Because the quandary was not resolved to our satisfaction there, it is revisited here. “Discoid lupus lesions can occur as the sole manifestation of lupus in the absence of systemic di…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

Inflammation Belizova Z. Inflammatory disease? Dermatopathol: Prac & Concep 2004;10(2):8, available at www.derm101.com B?er A, Phadke V, Ackerman AB. Inflammatory disease—In search of a definition of a term employed commonly. Dermatopathol: Prac…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Dandruff a Disease?

“Seborrheic dermatitis consists of a dry form (simple dandruff), with small dry to thick powdery scales . . .” White JW. Localized eczematous disease. In: Sams WM, Lynch PJ, eds. Principles and practice of dermatology. New York, NY: Ch…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

“Pruritic urticarial papules and plaques of pregnancy (PUPPP) was recently defined as an intensely pruritic cutaneous eruption occurring in the third trimester. . . . The overall picture was nonspecific and ranged from one suggestive of eryt…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

“On the basis of clinical, histological, and cellular kinetic observations, a separation of the major ichthyosiform dermatoses into four groups is proposed. Ichthyosis vulgaris patients have dry skin and fine scales on their trunk and extremi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

“Lupus erythematosus is a disorder associated with innumerable clinical signs and symptoms and a wide range of laboratory abnormalities; it shows a spectrum of varying prognoses ranging from a benign, solely cutaneous variant (localized disco…

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