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Histologic Diagnosis of Inflammatory Skin Diseases

Confusing Terms (to be Avoided Scrupulously)

APOPTOSIS [Gk. apo- (away from) + ptosis (a falling)]: Reputed to be a specific type of cell death in which dead cells are said to undergo fragmentation by implosion with subsequent phagocytosis of nuclear debris (Fig. 3.40). The process is claimed…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

“Lupus erythematosus is a disorder associated with innumerable clinical signs and symptoms and a wide range of laboratory abnormalities; it shows a spectrum of varying prognoses ranging from a benign, solely cutaneous variant (localized disco…

Histologic Diagnosis of Inflammatory Skin Diseases

Suggested Readings

Inflammation Belizova Z. Inflammatory disease? Dermatopathol: Prac & Concep 2004;10(2):8, available at www.derm101.com B?er A, Phadke V, Ackerman AB. Inflammatory disease—In search of a definition of a term employed commonly. Dermatopathol: Prac…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

…narily of a macule of conventional lichen planus, and pustular psoriasis, which is speeding up tremendously of a macule of guttate psoriasis. Degos’ disease, acral gangrene, i.e., of fingers and toes, and deep ulcers near internal malleoli are…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Perivasculitis?

“Pruritic urticarial papules and plaques of pregnancy (PUPPP) was recently defined as an intensely pruritic cutaneous eruption occurring in the third trimester. . . . The overall picture was nonspecific and ranged from one suggestive of eryt…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

In 1963, the year that one of us (A.B.A.) began a residency in dermatology, Walter Lever’s textbook, Histopathology of the Skin, was in its third edition and was deemed, universally, to be “the bible” of dermatopathology. To a firs…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Ichthyoses?

“On the basis of clinical, histological, and cellular kinetic observations, a separation of the major ichthyosiform dermatoses into four groups is proposed. Ichthyosis vulgaris patients have dry skin and fine scales on their trunk and extremi…

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