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Clinical Case Studies

Palmar Pustulosis

INITIAL PRESENTATION A 67-year-old otherwise healthy Filipino male with a history of episodic “scaling palms” presented with a bilaterally symmetric palmar pustular eruption that was unresponsive to oral antibiotics. The lesions started…

Clinical Case Studies

Extensive Actinic Damage

INITIAL PRESENTATION A 67-year-old Caucasian male presented with severe photodamage of his face and scalp and a history of multiple nonmelanoma skin cancers. (Figure 1) The patient had been treated with radiation for adolescent acne vulgaris. One ye…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

See Fig. 5.218 A&B. Figure 5.218 Vasculitis. A. Small vessel. B. Large vessel. Before a reasoned and reasonable method for diagnosis histopathologic of vasculitis in skin and subcutaneous fat can be formulated, a definition of vasculitis must…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Pustular Dermatitis

See Fig. 5.307 A&B. Figure 5.307 Pustular dermatitis. A. Infundibular. B. Surface epidermal. Although most pustules in skin are housed in infundibular epidermis (Fig. 5.308 A&B), many are lodged in surface epidermis (Fig. 5.309 A&B)….

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

In 1963, the year that one of us (A.B.A.) began a residency in dermatology, Walter Lever’s textbook, Histopathology of the Skin, was in its third edition and was deemed, universally, to be “the bible” of dermatopathology. To a firs…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.27.1A: Pustular dermatitis, infundibular + 10.27.1B: Perivascular and interstitial infiltrate of many neutrophils and innumerable eosinophils in infundibula and sebaceous lobules = Eosinophilic pustular folliculitis Because eosi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Colors Stereotypical for Diseases Specific?

“The color of skin lesions varies as already stated. … White lesions are rare excepting in exfoliative diseases, the scales of which are white. They usually result from loss of pigment. White spot disease, morphea, some of the idiopathi…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Cutaneous T-cell Lymphoma?

“There has been a tendency in recent years to phase out the term ‘mycosis fungoides’ and replace it with peripheral cutaneous T-cell lymphoma (CTCL).” Santa Cruz DJ, Hurt MA. Neoplasms of the skin. In: Sternberg SS, ed. Dia…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema marginatum

Erythema marginatum Synonyms Erythema marginatum rheumaticum Erythema annulare rheumaticum Presentation stereotypical Age and sex Children of both sexes who have rheumatic fever with carditis; rarely in adults Distribution of lesions Localized, es…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

Images 10.37.1A: Pustular dermatitis, infundibular + 10.37.1B: Numerous Demodex folliculorum and squames in a zone of suppuration = Suppurative infundibulitis of unknown cause Demodex, Pityrosporum, bacteria, sebum, squames, and cornified…

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