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Histologic Diagnosis of Inflammatory Skin Diseases

Embryologic Development

…e nipple, through which ostia it emerges on the surface of the skin. Parenthetically, the breast is not an organ per se, but a specialized region of skin and subcutaneous tissue. In sum, the germ in an embryo that gives rise to an infundibuloapocrine…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

…, a chronic inflammation or infiltration limited solely to the skin, and affecting chiefly the sebaceous glands and the parts immediately adjacent to them, ending in complete absorption, or in a cicatricial contraction of the skin, and not in any way…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo?

…lanosis of the genitalia, and certain pigmented spots on solar skin are simply different names for melanotic macule. Lentigo maligna is a euphemism for melanoma in situ on skin injured by the effects of sunlight, and acral-lentiginous melanoma is mer…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Subcorneal Blistering Diseases?

…oninfectious inflammatory disorders. In: Histopathology of the Skin, 1st ed. Philadelphia: J. B. Lippincott, 1949:58. “Subcorneal vesicles Miliaria crystallina Staphylococcal scalded skin syndrome Bullous impetigo Friction blister Pemphigus fo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus Versus Systemic Lupus Erythematosus?* I

…c lupus erythematosus can be regarded either as primarily with skin signs or secundarily after initial involvement of the skin. Typical forms of cutaneous lupus erythematosus are the subacute cutaneous and the discoid form.” Harr T, Bircher AJ…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Diabetic Dermopathy?

…ein kinase C overactivity. All of these processes occur in the skin, and the existence of a cutaneous diabetic microangiopathy has been well demonstrated. These microangiopathic changes are associated with abnormalities of skin perfusion.” Ngo…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Eosinophilic Cellulitis (Wells’ Syndrome)?

…ling juicy insect bites. . . . Histological examination of the skin biopsy showed the typical appearances of eosinophilic cellulitis and in addition numerous fungal hyphae were seen in the stratum corneum. Trichophyton rubrum was cultured from skin s…

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