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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Nuclear Atypia, Cytoplasmic Atypia, and Architectural Atypia?

…lasmic atypia.” Elder DE, Murphy GF. Benign melanocytic tumors (nevi). In: Atlas of Tumor Pathology: Melanocytic Tumors of the Skin. Washington, D.C.: Armed Forces Institute of Pathology, 1991; Third Series, Fascicle 2:81,83. “The word…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Langerhans’ Cell Granulomatosis?

“The cells of histiocytosis X [HX] have been designated “histiocytes” but the “ordinary” histiocytes encountered in healthy skin, in histiocytoma or various granulomatous processes are devoid of the granules. It could…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Lentigo Maligna?

…remalignant dysplasia).” Elder DE, Murphy GF. Malignant tumors (melanomas and related lesions). In: Atlas of Tumor Pathology: Melanocytic Tumors of the Skin. Washington, D.C.: Armed Forces Institute of Pathology, 1991; Third Series, Fascicle 2…

Differential Diagnosis in Dermatopathology

Apocrine (clear-cell) hidradenoma vs. Eccrine (poroid) hidradenoma

…ay become a plaque or upon it may develop a papule, nodule, or tumor. A papule may develop into a nodule or tumor. The surface of an elevated lesion of melanoma tends to be uneven. When a melanoma is no longer flat, it has capability to metastasize a…

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