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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Necrobiosis?

…ditions as disparate as erythema multiforme, leukocytoclastic vasculitis, and phototoxic dermatitis. No histopathologist considers that circumstance to be “necrobiosis.” The term necrobiosis figures in the title of two cutaneous diseases,…

Histologic Diagnosis of Inflammatory Skin Diseases

Erythema nodosum leprosum

…prosum avers that the mechanism for formation of lesions is a vasculitis of small vessels in a patient who has diffuse lepromatous leprosy. We, too, have stated that proposition, because on rare occasions careful scrutiny of sections of tissue from s…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…8221; of neutrophils, reminiscent of that of leukocytoclastic vasculitis. The many erythrocytes extravasated in the dermis indicate how severely venules have been compromised by the infectious process. 10.47.13A: Vesicular dermatitis, intraepid…

Differential Diagnosis in Dermatopathology

Subcutaneous granuloma annulare vs. Rheumatoid nodule

An arteritis in the subcutaneous fat manifested clinically at first by one or more red nodules that, in time, become ulcerated and heal with scars, usually on the posterior aspect of the legs of short, thick-legged women. No cause is usually found,…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Diabetic Dermopathy?

…y, nephropathy, and neuropathy, nor do we observe any sign of vasculitis. In their study of changes histopathologic of diabetic dermopathy, Binkley, Gerolds, and Stoughton found … thick-walled capillaries in the upper dermis. The endothelial ce…

Histologic Diagnosis of Inflammatory Skin Diseases

Pattern Analysis in Historical Perspective

…atitis (Fig. 5.6B) Nodular and diffuse dermatitis (Fig. 5.6C) Vasculitis (Fig. 5.6D) Intraepidermal vesicular and pustular dermatitis (Fig. 5.6E) Subepidermal vesicular dermatitis (Fig. 5.6F) Folliculitis and perifolliculitis (Fig. 5.6G) Fibrosing de…

Dermatology Practical & Conceptual

From the Dermatologikum Hamburg

…f neutrophils with variable degrees of leukocytoclasis but no vasculitis [1,4]. Fibrinoid degeneration of collagen, resembling the collagen changes present in rheumatoid nodules in a miniaturized form also has been reported [5]. The pattern of rheuma…

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