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Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

…with dermatomyositis, systemic sclerosis, and Sj?gren’s syndrome, but not with skin diseases like poikilodermatomyositis, morphea, or discoid lupus erythematosus. Just as dermatomyositis is a disease systemic with manifestations cutaneous (e.g….

Histologic Diagnosis of Inflammatory Skin Diseases

Precepts Adjunctive to the Algorithmic Method

…minds by way of analogy (albeit vaguely) of trytophan-myalgia syndrome, toxic oil syndrome, and Shulman’s syndrome, inflammatory conditions all. Last, if a histopathologist is stymied by particular findings met with in sections of tissue, repre…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Basic Patterns: Skin: Vasculitis

…the virus. Changes very early in the course of Sweet’s syndrome may be impossible to distinguish from those of leukocytoclastic vasculitis at an incipient stage of that process, i.e., prior to fibrin being deposited in the wall of venules. Unl…

Histologic Diagnosis of Inflammatory Skin Diseases

Identification of Distinctive but Nonspecific Findings Using High Magnification

…ic xanthogranuloma, and an infundibular cyst that ruptured. “CHURG-STRAUSS GRANULOMA” Neutrophils, nuclear “dust” of neutrophils, and, sometimes, eosinophils in a discrete locus of degenerated collagen in the reticular dermis, histiocytes in palisad…

Histologic Diagnosis of Inflammatory Skin Diseases

Darier’s disease and simulators of it

…thelial patterns are cellular granularity, flame figures, and Churg-Strauss granulomas. Each of those epithelial and nonepithelial patterns may be met with in several unrelated diseases, for example, epidermolytic acanthoma and bullous congenital ich…

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