Histologic Diagnosis of Inflammatory Skin Diseases

Precepts Adjunctive to the Algorithmic Method

…recommended here for diagnosis of inflammatory diseases of the skin and subcutaneous fat deserve mention. First, it is advantageous to examine sections of tissue, from the very outset, without reference to any clinical information, including history,…

Histologic Diagnosis of Inflammatory Skin Diseases

Lymphedema

Lymphedema Presentation stereotypical Age and sex Adults usually, women more than men Distribution of lesions Distal extremities, legs more than arms; genitalia episodically Arrangement of lesions Diffuse involvement of parts, e.g., elephantiasis In…

Histologic Diagnosis of Inflammatory Skin Diseases

Advantages of the Algorithmic Method

…f the inflammatory cells themselves, order can be brought to a subject about which, for so long, there was precious little of it, that morass giving rise to the all-too-common diagnosis (actually non-diagnosis) in times past of “chronic non-spe…

Dermatology Practical & Conceptual

A rare case of syphilis associated with renal and hepatic involvement

Abstract We present an unusual case of syphilis that despite starting treatment with penicillin has evolved with renal complications. Due to glomerulonephritis with nephrotic syndrome the case required shared care between the renal physician and der…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Anagen Effluvium?

…e cases could divide into two groups with regard to a delay in starting hair loss after administration of CBZ. In one group, the hair loss started within a week suggesting anagen effluvium and in another it started after two or three months suggestin…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Discoid Lupus Erythematosus versus Systemic Lupus Erythematosus? II

…ythematosus is a disorder associated with innumerable clinical signs and symptoms and a wide range of laboratory abnormalities; it shows a spectrum of varying prognoses ranging from a benign, solely cutaneous variant (localized discoid) through to a…

Histologic Diagnosis of Inflammatory Skin Diseases

Lupus erythematosus

Lupus erythematosus Synonyms Lupus erythematodes Presentation stereotypical Age and sex Young adult women especially, but sometimes neonates and older persons of both sexes. Distribution of lesions Often localized to sun-exposed sites such as the fa…

Histologic Diagnosis of Inflammatory Skin Diseases

Crohn’s disease

Crohn’s disease Synonyms Inflammatory bowel disease Regional ileitis Regional enteritis Chronic cicatrizing enteritis Presentation stereotypical Age and sex Young adults; slight predominance of women Distribution of lesions The poles of the ga…

Histologic Diagnosis of Inflammatory Skin Diseases

Bibliography

…133(12):1563-66. Moynahan EJ, Barnes PM. Zinc deficiency and a synthetic diet for lactose intolerance. Lancet 1973;676. Niemi KM, Anttila PH, Kanerva L, Johansson E. Histopathological study of transient acrodermatitis enteropathica due to decreased z…