Dermatology Practical & Conceptual

Hyperkeratotic necrobiosis lipoidica

…Necrobiosis lipoidica is a rare degenerative connective tissue disease of unclear etiology [3]. This disease is more common in females with a female-to-male ratio of approximately 3 to 1 [3]. It has been estimated that up to 65% of patients with necr…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…hic scars. “Porcelain white” scars are met with in Degosdisease and white atrophic scars sometimes mark the grave of pyoderma gangrenosum. “Thus, a vasculitis in the true sense does not exist in livedo vasculitis, as the de…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…elow the surface of the skin but is associated with induration Degosdisease presents itself as small and round lesions, but not as ones that are linear or whorled Findings histopathologic Vesicular lesions Early Superficial perivascular and…

Histologic Diagnosis of Inflammatory Skin Diseases

Epidermolysis bullosa simplex

Epidermolysis bullosa simplex Presentation stereotypical Age and sex Shortly after birth or during childhood and adolescence; both sexes affected Distribution of lesions Varies according to type of epidermolysis bullosa (see Variations clinical) Ind…

Histologic Diagnosis of Inflammatory Skin Diseases

Livedo vasculitis

…th Raynaud’s phenomenon, acrocyanosis, collagen-vascular diseases, obstructive arterial diseases, drug reactions, hyperviscosity states, hypertension, and lymphomas, the expressions of it morphologic, i.e., clinical and histopathologic, being t…

Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

…lipin antibodies) that have been found in lupus erythematosus, Degosdisease, and Sneddon’s syndrome. Thrombotic thrombocytopenic purpura occurs in conjunction with thrombocytopenia, microvascular hemolytic anemia, neurologic abnormaliti…