Dermatology Practical & Conceptual

Hyperkeratotic necrobiosis lipoidica

…ecrobiosis lipoidica is a rare degenerative connective tissue disease of unclear etiology [3]. This disease is more common in females with a female-to-male ratio of approximately 3 to 1 [3]. It has been estimated that up to 65% of patients with necro…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Atrophie Blanche?

…ic scars. “Porcelain white” scars are met with in Degosdisease and white atrophic scars sometimes mark the grave of pyoderma gangrenosum. “Thus, a vasculitis in the true sense does not exist in livedo vasculitis, as the des…

Histologic Diagnosis of Inflammatory Skin Diseases

Incontinentia pigmenti

…low the surface of the skin but is associated with induration Degosdisease presents itself as small and round lesions, but not as ones that are linear or whorled Findings histopathologic Vesicular lesions Early Superficial perivascular and…

Histologic Diagnosis of Inflammatory Skin Diseases

Epidermolysis bullosa simplex

…ds and feet, epidermolysis bullosa manum et pedum aestivalis) Dowling-Meara type (epidermolysis bullosa simplex herpetiformis) Ogna type The types usually listed under the heading of epidermolysis bullosa simplex are as follows: Localized (Weber-Co…

Histologic Diagnosis of Inflammatory Skin Diseases

Livedo vasculitis

…us (superficial morphea) and of malignant atrophic papulosis (Degosdisease). Some authors contend that livedo vasculitis is a vasculopathy and not a true vasculitis. We eschew the term vasculopathy because it is bereft of meaning as terms suc…

Histologic Diagnosis of Inflammatory Skin Diseases

Disseminated intravascular coagulopathy

…ipin antibodies) that have been found in lupus erythematosus, Degosdisease, and Sneddon’s syndrome. Thrombotic thrombocytopenic purpura occurs in conjunction with thrombocytopenia, microvascular hemolytic anemia, neurologic abnormalitie…