Histologic Diagnosis of Inflammatory Skin Diseases

Nephrogenic fibrosing dermopathy

…ers in association with abundant mucin. Adipocytes adjacent to septa in the subcutaneous fat sometimes were atrophic, and, rarely, histiocytic giant cells containing clefts like those of Mieschers radial granulomas, characteristic usually of e…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Satellite, in Transit, Regional, and Distant Metastases?

sentinel node biopsy was a useless exercise and doomed to the same ash-heap on which is strewn so many other egregious misconceptions about therapy for melanoma, ranging from amputation of limbs to the Miescher therapy with grenz rays for “len…

Resolving Quandaries in Dermatology, Pathology & Dermatopathology

Benign and Malignant Cells?

st is the recognition that cells of a benign neoplasm may have startlingly large and pleomorphic nuclei, e.g., those of some Spitz nevi and of ancient Mieschers nevi, and in reverse, cells of some malignant neoplasms may display remarkably sma…

Histologic Diagnosis of Inflammatory Skin Diseases

Elastosis perforans serpiginosa

…tol 1968;97:381-93. Mehta RK, Burrows NP, Payne CM, Mendelsohn SS, Pope FM, Rytina E. Elastosis perforans serpiginosa and associated disorders. Clin Exp Dermatol 2001;26:521-24. Miescher G. Elastoma intrapapillare perforans verruciforme. Dermatologic…

Histologic Diagnosis of Inflammatory Skin Diseases

Images

…titial dermatitis, granulomatous + 10.43.19B: Histiocytes, some of them multinucleate and containing asteroid bodies, splayed among collagen bundles, and lymphocytes huddled around venules = Mieschers granuloma of the face This condition r…

Histologic Diagnosis of Inflammatory Skin Diseases

Granuloma annulare

…ules on the trunk mainly, but also on the extremities; lesions sometimes are found in photodistribution; the condition may be associated with diabetes mellitus. Mieschers granuloma of the face, a solitary annular plaque typically on the forehe…

Histologic Diagnosis of Inflammatory Skin Diseases

Trichotillomania

…ted twisting to and fro. That finding alone, however, does not signify trichotillomania. For example, persons may twist in that manner a hair shaft that emerges from a congenital melanocytic nevus, especially of Mieschers type, and if that les